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1.
Immunogenetic studies of juvenile dermatomyositis: HLA-DR antigen frequencies.
Friedman, J M; Pachman, L M; Maryjowski, M L; Radvany, R M; Crowe, W E; Hanson, V; Levinson, J E; Spencer, C H.
Arthritis Rheum ; 26(2): 214-6, 1983 Feb.
Article in English | MEDLINE | ID: mdl-6572047

Subject(s)
Dermatomyositis/immunology , Histocompatibility Antigens Class II/analysis , Adolescent , Adult , Black People , Child , Child, Preschool , Dermatomyositis/diagnosis , HLA-DR Antigens , Hispanic or Latino , Humans , Infant
2.
Immunogenetic studies of juvenile dermatomyositis. HLA antigens in patients and their families.
Friedman, J M; Pachman, L M; Maryjowski, M L; Jonasson, O; Battles, N D; Crowe, W E; Fink, C W; Hanson, V; Levinson, J E; Spencer, C H; Sullivan, D B.
Tissue Antigens ; 21(1): 45-9, 1983 Jan.
Article in English | MEDLINE | ID: mdl-6601315

ABSTRACT

Typing for HLA-A and -B antigens was performed on 87 children with definite juvenile dermatomyositis (JDMS). A significantly increased frequency of HLA-B8 (estimated relative risk = 2.8, Pc less than 0.01) was observed among White patients, but not among Blacks or Latin Americans with JDMS. No abnormality of HLA haplotype segregation was observed among 38 healthy siblings of the JDMS probands.


Subject(s)
Dermatomyositis/immunology , HLA Antigens/genetics , Adolescent , Adult , Black People , Child , Child, Preschool , Dermatomyositis/genetics , Female , HLA-A Antigens , HLA-B Antigens , HLA-B8 Antigen , Humans , Infant , Latin America/ethnology , Male , White People
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