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1.
Radiats Biol Radioecol ; 34(1): 85-90, 1994.
Article in Russian | MEDLINE | ID: mdl-8148984

ABSTRACT

The equidosimetric principle for modelling of general nonuniform radiation effects has been formulated. The method for realistic modelling of the effects by dynamic control of radiation exposure of two basic critical systems (active bone marrow and intestine) has been developed.


Subject(s)
Computer Simulation , Models, Biological , Radiobiology/methods , Whole-Body Irradiation , Animals , Dose-Response Relationship, Radiation , Humans , Mathematics , Mice , Radiation Tolerance , Rats , Software , Species Specificity
2.
Med Radiol (Mosk) ; 36(10): 44-7, 1991.
Article in Russian | MEDLINE | ID: mdl-1943556

ABSTRACT

The authors describe a new method of dosimetric design of partial radiation exposures (PRE) in radiobiological experiments on rodents, using a universal lead component screen. A choice of a shape of irradiation fields and location of screen elements on the body of an animal is done according to a CT program, developed in the IBM PC version. This method helps to standardize physicotechnical support of PRE in radiobiological experiments.


Subject(s)
Radiation Protection , Radiotherapy Dosage , Thermoluminescent Dosimetry , Animals , Radiotherapy Planning, Computer-Assisted , Rats
3.
Med Radiol (Mosk) ; 36(8): 47-8, 1991.
Article in Russian | MEDLINE | ID: mdl-1890943

ABSTRACT

The paper is concerned with the results of dose measurements on a uterine phantom under the conditions close to those of the practice of radiotherapy of endometrial cancer patients using the AGAT-B unit. Comparison of experimental and rated dose values made it possible to find points of particular clinical alertness as well as a point of the control of accuracy of dose formation during a radiotherapeutic session.


Subject(s)
Brachytherapy/methods , Models, Structural , Patient Care Planning/methods , Uterine Neoplasms/radiotherapy , Brachytherapy/instrumentation , Cobalt Radioisotopes/therapeutic use , Female , Humans , Radiotherapy Dosage , Thermoluminescent Dosimetry
4.
Med Radiol (Mosk) ; 34(4): 23-6, 1989 Apr.
Article in Russian | MEDLINE | ID: mdl-2709958

ABSTRACT

The authors proposed a method of dosimetric planning in intracavitary irradiation taking into account the individual features of a patient, including the status of the uterus during the introduction of radiation sources into its cavity. To simulate the dynamics of a resultant uterus shift a special device was developed to obtain information required for individual planning. The proposed method is aimed at the prevention of undesirable radiation reactions and complications in healthy organs.


Subject(s)
Brachytherapy , Genital Neoplasms, Female/radiotherapy , Female , Humans , Radiotherapy Dosage
5.
Med Radiol (Mosk) ; 32(5): 24-7, 1987 May.
Article in Russian | MEDLINE | ID: mdl-3295454

ABSTRACT

The paper is concerned with the results of experimental dosimetric studies on an anthropomorphic phantom using thermoluminescent dosimetry at the site of the joining of large fields of complex shape simulating total irradiation of the lymphatic collectors. The studies demonstrated the appropriateness of the joining at a distance of 1 cm between the fields. In such a variant adequate irradiation of the lymphatic system was achieved whereas an increase in a distance between the fields resulted in a risk of recurrence in under-irradiated areas without a significant decrease in radiation dose exposure to healthy organs and tissues.


Subject(s)
Lymphatic System/radiation effects , Radiotherapy Dosage , Whole-Body Irradiation , Humans , Models, Structural
6.
Med Radiol (Mosk) ; 30(11): 58-63, 1985 Nov.
Article in Russian | MEDLINE | ID: mdl-4068948

ABSTRACT

A study was made of change of the spectrum (spectral transformation) of x-ray radiation while passing through the soft tissue. Thirty-two depth spectra computed by the Monte-Carlo method and 16 experimentally measured spectra including 9 depth spectra taken from literature, were analysed. A method of the calculation of an absorbed dose in the red bone marrow with account of spectral transformation was described. It was shown that neglect of this factor caused regular underestimation of the assessment of medullary doses, patients were exposed to, during x-ray procedures. The error can reach 40% for doses at local points of the red bone marrow and 1-7% for mean medullary doses with regard to the type of x-ray procedure and regimen of its performance.


Subject(s)
Bone Marrow , Radiation Dosage , Radiography , Humans , Technology, Radiologic
7.
Med Radiol (Mosk) ; 30(9): 50-6, 1985 Sep.
Article in Russian | MEDLINE | ID: mdl-2931570

ABSTRACT

The Soviet and Finnish authors presented a short description of two computer methods to determine doses in the patients' organs. Based on the general principles, such as a semiempirical mathematical description of dose fields and a realistic anthropomorphous phantom, these methods differed significantly in the algorithms used and ways of solving specific problems. The comparison of these methods and calculated dose values with the results of experimental measurements on the phantom showed a good convergence of the results. The divergence of calculated and experimental data by the values of the mean absorbed doses in the organs did not exceed +/- 35%. The advantages and prospects of the use of the computer methods for the evaluation of doses received by patients, were demonstrated.


Subject(s)
Radiography/methods , Absorption , Evaluation Studies as Topic , Finland , Humans , Mathematics , Models, Structural , Radiation Dosage , Russia , Software
8.
Med Radiol (Mosk) ; 30(1): 48-51, 1985 Jan.
Article in Russian | MEDLINE | ID: mdl-3968997

ABSTRACT

Basing on the utilization of the benefit-injury concept the authors put forward an approach to the substantiation of permissible errors in the values of the mean doses intended for the patient's critical organs in x-ray examination. It was shown that in the elaboration of methods to determine the mean tissue doses one should aim at reaching a mean quadratic error of +/- 30% in their values.


Subject(s)
Radiation Dosage , Radiography/standards , Humans , Risk
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