Comparison of satisfaction degree of patients treated at the Inflammatory Bowel Disease Unit (IBDU) of Hospital Universitario 12 de Octubre between previous face-to-face care and telephone care during the COVID-19 pandemic.

The aim of the IBDU is to provide comprehensive care for patients with IBD (1,2). During the COVID-19 pandemic, telephone medical consultations and telemedicine training sessions were implemented to ensure patient safety (3). The aim of this study was to determine whether there was a difference in the degree of satisfaction between face-to-face and telephone care, as well as in the annual patient sessions.

Stem cell therapy in inflammatory bowel disease: A promising therapeutic strategy?

Inflammatory bowel diseases are inflammatory, chronic and progressive diseases of the intestinal tract for which no curative treatment is available. Research in other fields with stem cells of different sources and with immunoregulatory cells (regulatory T-lymphocytes and dendritic T-cells) opens up new expectations for their use in these diseases. The goal for stem cell-based therapy is to provide a permanent cure. To achieve this, it will be necessary to obtain a cellular product, original or genetically modified, that has a high migration capacity and homes into the intestine, has high survival after transplantation, regulates the immune reaction while not being visible to the patient's immune system, and repairs the injured tissue.

[Intestinal leishmaniasis and Sézary syndrome: endoscopic diagnosis]. / Leishmaniasis intestinal y síndrome de Sézary: diagnóstico endoscópico.

Sézary syndrome is a non-Hodgkin's lymphoma of cutaneous origin that provokes severe cellular immunosuppression leading to greater susceptibility to opportunistic infections. We present the case of a male patient with a diagnosis of Sézary syndrome complicated by visceral leishmaniasis and Mycobacterium avium complex coinfection, with intestinal involvement of both pathogens -an exceptional finding in the absence of HIV infection. The diagnosis was confirmed by bone marrow biopsy and oral endoscopy with intestinal biopsy. Because of the severity of the infection and the failure of conventional treatment, miltefosine, a new antiparasitic agent still under investigation, was administered with favorable response. However the patient developed fatal pneumonia.

Leishmaniasis intestinal y síndrome de Sézary: diagnóstico endoscópico / Intestinal leishmaniasis and Sézary syndrome: endoscopic diagnosis

El síndrome de Sézary es un linfoma no hodgkiniano de origen cutáneo que provoca una inmunosupresión celular grave y, por ello, una mayor susceptibilidad a adquirir infecciones oportunistas. Presentamos el caso de un paciente diagnosticado de un síndrome de Sézary, complicado con leishmaniasis visceral y coinfección por Mycobacterium avium complex, con afección intestinal por ambos patógenos, hecho excepcional en ausencia de la infección por el virus de la inmunodeficiencia humama. La biopsia de la médula ósea y la endoscopia oral con toma de biopsias del intestino confirmaron el diagnóstico. La gravedad del cuadro y el fracaso de los tratamientos convencionales obligaron a emplear miltefosina, un nuevo fármaco antiparasitario en fase de investigación, con el que se obtuvo una respuesta favorable. Sin embargo, el cuadro se complicó con una neumonía de evolución fatal

Sézary syndrome is a non-Hodgkin's lymphoma of cutaneous origin that provokes severe cellular immunosuppression leading to greater susceptibility to opportunistic infections. We present the case of a male patient with a diagnosis of Sézary syndrome complicated by visceral leishmaniasis and Mycobacterium avium complex coinfection, with intestinal involvement of both pathogens ­an exceptional finding in the absence of HIV infection. The diagnosis was confirmed by bone marrow biopsy and oral endoscopy with intestinal biopsy. Because of the severity of the infection and the failure of conventional treatment, miltefosine, a new antiparasitic agent still under investigation, was administered with favorable response. However the patient developed fatal pneumonia