ABSTRACT
Leukocytic index of intoxication (LII), number of leukocytes and lymphocytes in blood were compared with clinical symptoms and histological examination of removed organs in patients with acute pyodestructive diseases of abdominal organs. Correlation between LII and inflammation severity was revealed. It is also demonstrated that high LII with low level of lymphocytes is a negative prognostic sign.
Subject(s)
Abdomen, Acute/diagnosis , Appendicitis/diagnosis , Cholecystitis, Acute/diagnosis , Peritonitis/diagnosis , Abdomen, Acute/blood , Abdomen, Acute/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Appendicitis/blood , Appendicitis/pathology , Appendix/pathology , Cholecystitis, Acute/blood , Cholecystitis, Acute/pathology , Data Interpretation, Statistical , Gallbladder/pathology , Humans , Inflammation/diagnosis , Intestines/pathology , Leukocyte Count , Lymphocyte Count , Middle Aged , Models, Theoretical , Peritoneum/pathology , Peritonitis/blood , Peritonitis/pathology , Prognosis , Severity of Illness Index , Suppuration/diagnosisABSTRACT
Studies of the leukocytic intoxication index (LII), leukocytes, and lymphocytes in patients with inflammatory, purulent, and pyodestructive diseases of the abdomen, lung, and soft tissues at the height of disease have ascertained that LII progressively increased and the relative count of lymphocytes decreased with the worse health status in all groups of patients, particularly in ineffectively treated patients who subsequently died. However, in these patients, the absolute count of lymphocytes did not always tend to decrease. The persistent high LII concurrent with lymphocytopenia indicated a poor prognosis. Leukocytes had less pronounced changes in this respect.
Subject(s)
Infections/blood , Severity of Illness Index , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Infections/diagnosis , Infections/pathology , Inflammation/blood , Inflammation/diagnosis , Inflammation/pathology , Leukocyte Count , Male , Middle Aged , Prognosis , Suppuration/blood , Suppuration/diagnosis , Suppuration/pathologyABSTRACT
While tumors stage III-IV of hollow organs involved lowered lymphocyte count matched by relatively high leukocyte index of intoxication, those parameters remained unchanged in parenchymatous cancer. Changes in lymphocyte count were both rarer and more irregular in all tumor sites. Similar changes occurred in post-operative pyo-destructive complications of hollow organs. This phenomenon may be instrumental in diagnosis of complication of both primary and postoperative pathology and assessment of surgical damage.
Subject(s)
Leukocyte Count , Lymphocyte Count , Neoplasms/blood , Adult , Aged , Breast Neoplasms/blood , Case-Control Studies , Esophageal Neoplasms/blood , Female , Humans , Intestinal Neoplasms/blood , Kidney Neoplasms/blood , Lung Neoplasms/blood , Male , Middle Aged , Neoplasms/diagnosis , Neoplasms/surgery , Ovarian Neoplasms/blood , Stomach Neoplasms/bloodABSTRACT
The leukocytic index of intoxication (LII), hemoglobin, leukocytes, and lymphocytes were studied in patients with inflammatory, purulent, and pyodestructive diseases of the abdomen, lung, and soft tissues. It was shown that Lll progressively increased and the levels of lymphocytes decreased as the states deteriorated in all groups of patients, particularly in those who died due to ineffective treatment. This all testifies to the diagnostic and predictive value of these parameters and they may be wider used in the treatment of patients with inflammatory, purulent, and pyodestructive diseases at various sites. This is indicated by the values obtained by the end of treatment of patients.
Subject(s)
Inflammation/diagnosis , Poisoning/diagnosis , Severity of Illness Index , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Inflammation/blood , Leukocyte Count , Male , Middle Aged , Poisoning/blood , Prognosis , SuppurationABSTRACT
A formula was suggested to determine the leukocytic index of intoxication (LII), which is a correlation between the level of neutrophils and the content of other cells in the blood leukocytic composition. The above formula was used to estimate the minimal, maximal and mean LII indices in patients, who had no inflammatory or purulent pathologies, i.e. normal indices, which respectively amounted to 1, 3 and 1.9. Such approach to composing a formula is in line with the specific features of vital activity, unlike Ya.Ya. Kalf-Kalif formula, which (when it was composed) it was added a number of coefficients. The application of the offered formula to determine the LII at acute appendicitis showed that the more severe an acute appendicitis was so much the LII increase was more intensive. It is noteworthy, that the high LII indices did not always correlate with an increased quantity of blood leukocytes. The above stated proves that the offered LII formula can be used in practice.
Subject(s)
Inflammation/blood , Leukocyte Count/methods , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Mathematics , Middle Aged , Reference Values , SuppurationABSTRACT
The authors describe a method of conducting the jejunum for hepaticojejunal anastomosis behind the colon and stomach. The authors show the advantages of the method confirmed by clinical observations and by investigations of corpses.
