[Modification of the mitochondrial membrane from the rat liver by synthetic phospholipids]. / Modifikatsiia mitokhondrial'noi membrany iz pecheni krys sinteticheskimi fosfolipidami.

Reconstruction of rat liver mitochondrial membrane by means of synthetic phospholipids enabled to improve the conception on the role of lipids in formation of monoamine oxidase multiple forms as well as elucidated the functions of mitochondrial membrane itself, which contains a tightly-mounted MAO, in regulation of biogenic amines enzymatic oxidation. The data obtained excluded the deciding importance of phospholipids in formation of two types of monoamine oxidases and corroborated the hypothesis on the active role of mitochondrial membrane in enzymatic reactions of tightly-mounted MAO as well as these data suggest that alterations in conformational mobility of the membrane hydrophobic sites shifted distinctly the kinetics of the enzymatic reaction.

[Mutagenic action of platinum and palladium compounds on bacteria]. / Izuchenie mutagennogo deistviia soedinenii platiny i palladiia na bakterii.

Platinum complex compounds are shown to cause mutations in S. typhimurium strains, TA-100 and TA-98 bearing plasmid pKM-101 but not in isogenic strains TA-1535 and TA-1538 lacking the plasmid. The mutagenic action depended on the ligand nature in the complex and did not depend on the extent of the central atom oxidation. No mutagenic activity of the palladium compounds tested was found.