ABSTRACT
Clear cell carcinoma (CCL) arising in the lower urinary tract is unusual and we report the cytohistologic findings of three cases retrieved from our files. All patients presented with bleeding, and the tumors were localized in either the urethra or bladder base. Filter and cytocentrifuge preparations of the urine were studied and all cases displayed numerous scattered aggregates or single tumor cells in an inflammatory background. The enlarged cells had abundant clear, wispy cytoplasm with discrete vacuolation. Hobnail and signet ring cells were apparent. The nuclei had granular to vesicular chromatin with prominent often multiple nucleoli. The tumors were histologically distinctive and typically had a tubulocystic configuration with varying proportions of papillary and diffuse patterns. One patient has died of metastatic cancer and two are presently free of tumor. The cytohistologic features of this cancer are characteristic and from our review we conclude that this lesion can be diagnosed by cytologic means.
Subject(s)
Adenocarcinoma, Clear Cell/pathology , Urethral Neoplasms/pathology , Urinary Bladder Neoplasms/pathology , Adenocarcinoma, Clear Cell/urine , Cytodiagnosis , Female , Humans , Male , Middle Aged , Urethral Neoplasms/urine , Urinary Bladder Neoplasms/urineABSTRACT
We describe the cases of two asymptomatic patients who had carpet beetle larval parts in routine cervical Pap smears. The diagnosis was made by finding pathognomonic hastisetae in the smears. The evidence suggests that contamination occurred at or around the time of sampling.
