ABSTRACT
A case of a healthy 23-year-old woman is reported with cytomegalovirus mononucleosis as a result of infection of cytomegalovirus probably primary. The patient presented with symptoms of generalized adenopathy, migratory arthralgias and arthritis, hepatosplenomegaly, long lasting rash as well as complications of pneumonia and myocarditis. Because on histopathological examination of lymph node the Hodgkin-Reed-Sternberg-like cells were found a misdiagnosis of Hodgkin's disease was initially made. After about 8 weeks period there was a complete recovery. The current problems related to cytomegalovirus infection are presented.
Subject(s)
Cytomegalovirus Infections/diagnosis , Infectious Mononucleosis/diagnosis , Adult , Diagnostic Errors , Female , Hodgkin Disease/diagnosis , Humans , Lymph Nodes/pathology , Reed-Sternberg Cells/pathologyABSTRACT
In 66 patients with peptic ulcer (11 with gastric ulcer, 55 with duodenal ulcer, 19 women, 47 men) the serum concentrations of prolactin, dehydrocholic acid and gastrin were determined. The studies were repeated after treatment with ranitidine: in 50 patients after three weeks and in 40 patients after another 30 days. During the first period ranitidine 2 x 150 mg was administered, while during the second period the dose was 1 x 150 mg. The results were compared with those obtained from 120 healthy subjects. Before starting the treatment prolactin levels were significantly higher than those in the control group. During the treatment a significant decrease of the levels was observed. Similar changes of prolactin concentrations were found in the group of 39 men with duodenal ulcer isolated from the studied patients, who were compared with a group of 50 healthy men. It was not found that the development of peptic ulcer and the treatment with ranitidine exerted and effect on the changes of gastrin and dehydrocholic acid concentrations.
Subject(s)
Anti-Ulcer Agents/therapeutic use , Gastrins/blood , Glycocholic Acid/blood , Histamine H2 Antagonists/therapeutic use , Peptic Ulcer/blood , Peptic Ulcer/drug therapy , Prolactin/blood , Ranitidine/therapeutic use , Adult , Case-Control Studies , Female , Humans , Male , Middle Aged , Time Factors , Treatment OutcomeABSTRACT
Three cases are presented of hereditary spherocytosis that occurred in one family. In one of those cases the presence of monoclonal IgG lambda protein was stated. This protein's level has not increased for 8 year of observation. The latest pathogenetic theories of hereditary spherocytosis are presented as well as the possibility of its coexistence with other diseases.
