ABSTRACT
Imiquimod 5% cream, an immune response modifier licensed for treatment of external ano-genital warts and superficial basal cell carcinomata, is known to cause local erythema, oedema and, rarely, exacerbation of psoriasis. We describe a case of exacerbation of eczema following application of this cream in a man with penile warts.
Subject(s)
Adjuvants, Immunologic/adverse effects , Aminoquinolines/adverse effects , Condylomata Acuminata/drug therapy , Drug Eruptions/etiology , Eczema/chemically induced , Penile Diseases/drug therapy , Adult , Humans , Imiquimod , Male , OintmentsABSTRACT
Between 1962 and 1994, 32 isolates of Trichophyton verrucosum from cases of tinea corporis, tinea faciei and tinea capitis were referred to the Mycology Reference Laboratory of the Microbiological Diagnostic Unit at The University of Melbourne, Victoria, Australia. Patients had presented at clinics in metropolitan Melbourne and country towns in the State of Victoria, Australia. They included dairy and cattle farmers, a slaughterman who worked in an abattoir, a veterinary tutor and children who lived on farms. Many patients lived in one of the three dairy farming areas of Victoria. A few lived in the outer suburbs of Melbourne. One cattle farmer came from south-east New South Wales. Specimens were not received for examination from animal contacts of the patients. The only patient from overseas was a boy from Lebanon. The literature recording human infections due to T. verrucosum in Australia is reviewed.
Subject(s)
Cattle Diseases/microbiology , Tinea/diagnosis , Zoonoses , Abattoirs , Adolescent , Adult , Animal Husbandry , Animals , Cattle , Child , Child, Preschool , Facial Dermatoses/microbiology , Female , Humans , Male , Occupational Diseases/diagnosis , Tinea Capitis/diagnosis , Trichophyton/classification , Trichophyton/growth & development , Trichophyton/isolation & purification , Veterinary Medicine , VictoriaABSTRACT
From 1963 to 1995, twenty isolates of Trichophyton violaceum from cases of tinea capitis and tinea corporis were referred to the Mycology Reference Laboratory of the Microbiological Diagnostic Unit at the University of Melbourne (Parkville, Victoria, Australia). The patients had presented at clinics in metropolitan Melbourne and country towns in the state of Victoria, Australia. Most patients were immigrants from the Mediterranean region or were Australian Aborigines. The most recent isolates of T. violaceum came from Ethiopian immigrants. Details of these twenty case histories are presented. The changing global distribution of infections due to T. violaceum is noted. The literature recording infections due to T. violaceum in Australia is reviewed.
Subject(s)
Native Hawaiian or Other Pacific Islander , Tinea Capitis/ethnology , Trichophyton/isolation & purification , Adolescent , Australia/epidemiology , Child , Child, Preschool , Emigration and Immigration , Ethiopia , Female , Greece , Humans , Incidence , Italy , Male , Risk Factors , Saudi Arabia , Tinea Capitis/diagnosis , Tinea Capitis/epidemiology , TurkeyABSTRACT
A patient from Cambodia presented at a hospital in Melbourne with a persistent subcutaneous abscess of the right buttock. Septate fungal hyphae were seen in biopsy tissue. Lasiodiplodia theobromae was isolated and identified by the formation of pycnidia that produced typical conidia. The abscess was managed by drainage and debridement only. We briefly review the history and importance of the fungus as a wound parasite in tropical horticulture and its relatively rare occurrence in human infections. The significance of this fungus in Australian horticulture and its potential as an opportunistic human pathogen is noted. This paper records the first isolation of L. theobromae from a human lesion in Australia and the second isolation from a subcutaneous lesion worldwide.
Subject(s)
Abscess/microbiology , Dermatomycoses/microbiology , Fungi/isolation & purification , Abscess/pathology , Adult , Australia , Biopsy , Cambodia/ethnology , Dermatomycoses/pathology , Female , Fungi/classification , Fungi/growth & development , Humans , Skin Diseases/microbiology , Skin Diseases/pathologyABSTRACT
Fungal isolates from the peritoneal cavity, kidney and liver, respectively, of three premature Australian babies are described as Rhizopus azygosporus. All three babies died. This is the first report as far as we know of the isolation of this fungus from human infections. It has previously been isolated only from Indonesian tempeh. The source of these infections was not determined. Rhizopus azygosporus is closely related to R. microsporus var. microsporus, var. rhizopodiformis and var. chinensis. The occurrence of azygospores in Zygomycetes and the taxonomic position of R. azygosporus are discussed.
Subject(s)
Mucormycosis/microbiology , Rhizopus/isolation & purification , Fatal Outcome , Humans , Infant , Microscopy, Electron, Scanning , Mucormycosis/pathology , Rhizopus/classification , Rhizopus/cytology , Rhizopus/growth & development , Spores, Fungal/cytology , Spores, Fungal/isolation & purificationABSTRACT
The isolation of Scytalidium hyalinum from the toe nail of a patient from Melbourne is reported. This is the first record of the isolation of this fungus from a clinical site in Australia. A brief history is given of the occurrence of Scytalidium hyalinum and the related fungus, Hendersonula toruloidea, in tinea pedis and tinea unguium in immigrants to the United Kingdom from tropical countries. Attention is drawn to the possible presence of these dermatophyte-like infections in patients in Australia.
Subject(s)
Foot Dermatoses/complications , Nails, Ingrown/etiology , Onychomycosis/complications , Aged , Arthrodermataceae , Foot Dermatoses/microbiology , Humans , Male , Mitosporic Fungi , Onychomycosis/microbiologyABSTRACT
A case of zygomycosis due to Rhizopus microsporus variety microsporus in a patient who was receiving haemodialysis is described. This infection resulted in amputation of the right hand. Criteria to identify the fungus are presented. The pathogenesis and treatment of zygomycosis are discussed.
Subject(s)
Cellulitis/microbiology , Hand/surgery , Mucormycosis/complications , Amphotericin B/therapeutic use , Amputation, Surgical , Cellulitis/surgery , Female , Humans , Middle Aged , Mucormycosis/drug therapy , Mucormycosis/pathology , Renal Dialysis , Rhizopus/isolation & purificationABSTRACT
The sudden death occurred of a captive Estuarine crocodile hatchling (Crocodylus porosus). On autopsy, granuloma-like lesions were seen in the liver, left lung and spleen, and branching, septate fungal hyphae were observed in sections of liver and spleen. The fungus isolated from the liver showed characteristics of both Paecilomyces lilacinus and Paecilomyces marquandii but was closer to the former species. This is apparently the first report of the isolation of this fungus from a reptile in Australia.
