[Correlation of some parameters of carbohydrate metabolism and central hemodynamics in the early stages of circulatory insufficiency in patients with ischemic heart disease]. / Sootnoshenie nekotorykh pokazatelei uglevodnogo obmena i parametrov tsentral'noi gemodinamiki na rannikh stadiiakh nedostatochnosti krovoobrashchenia u bol'nykh ishimicheskoi bolezn'iu serdtsa.

The study was undertaken to examine central hemodynamic and carbohydrate metabolic parameters in patients with coronary heart disease (with or without signs of chronic heart failure, Stages I and IIA). The changes in carbohydrate metabolism in CHD patients were detected earlier than those in central hemodynamics. In patients with Stage I heart failure, who had normal resting hemodynamic parameters, metabolic parameters were indicative of abnormalities in carbohydrate metabolism: there was a reduction in carbohydrate tolerance and red blood cell release of insulin in response to glucose load and an increase in blood immunoreactive insulin, erythrocytic glucose-6-phosphate dehydrogenase activity and greater adrenalin- and insulin-containing erythrocytes. It is suggested that it is advisable to determine the above parameters of carbohydrate metabolism in patients with coronary heart disease.

[The level of blood insulin and the glycolytic activity of the blood in patients with ischemic heart disease]. / Uroven' insulinemii i glikoliticheskaia aktivnost' krovi bol'nykh ishemicheskoi bolezn'iu serdtsa.

Disorders of the glucose tolerance test (diabetic and borderline glycemic curves) were revealed in 49% of patients with ischemic heart disease. These patients showed hyperinsulinemia. The glycolytic activity of the blood, especially in patients with circulatory insufficiency, was increased evidencing lagging behind of the aerobic phase of carbohydrate oxidation from the glycolytic splitting. Disorders of the carbohydrate metabolism in these patients is caused by relative insulin insufficiency and tissue hypoxia.