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1.
Vestn Oftalmol ; 136(6. Vyp. 2): 133-141, 2020.
Article in Russian | MEDLINE | ID: mdl-33371641

ABSTRACT

The search for optimal design and material of the intraocular lens (IOL) that would prevent posterior capsule opacification (PCO) is still a relevant problem. PURPOSE: To compare the influence of three models of hydrophobic acrylic IOLs on the development of PCO within one year after phaco surgery. MATERIAL AND METHODS: The study included 72 patients (91 eyes) who were followed up for 12 months after implantation of one of three models of posterior chamber hydrophobic acrylic IOLs: MIOL-2 (Reper-NN, Russia, 24 eyes, 1st group), SA60AT and US60MP (Alcon, USA, 41 and 26 eyes, 2nd and 3rd groups, respectively). Posterior capsule images were taken and then processed with the EPCO 2000 (Evaluation of Posterior Capsular Opacification) software. The area of posterior capsule adjacent to the center of IOL's optic of 4.0 mm in diameter was estimated. PCO score was calculated as the weighted sum of opacification areas multiplied by the degree (from 0 to 4). RESULTS: Within 1 year of the follow-up, mean visual acuity was at least 1.0 (20/20). Significant PCO progression was observed as early as 3 months after surgery. Despite that, opacification density in all three groups at every follow-up visit did not exceed grade 2; maximal PCO score (0.0315, median) was seen 12 month after surgery in the 1st group. At the same time, differences in PCO score between the groups were not significant. Nd:YAG laser posterior capsulotomy was performed only in one patient from the 1st group 12 month after surgery. Difference in the percentage of clear posterior capsules was significant only 12 month after surgery between the 1st and 3rd groups (p=0.024). CONCLUSION: All three models of hydrophobic acrylic IOLs showed comparably high vision outcomess during 12 months of the follow-up with somewhat better PCO score and percentage of clear posterior capsules in eyes with US60MP.


Subject(s)
Capsule Opacification , Cataract , Lenses, Intraocular , Phacoemulsification , Acrylic Resins , Capsule Opacification/diagnosis , Capsule Opacification/etiology , Capsule Opacification/prevention & control , Cataract/diagnosis , Cataract/etiology , Humans , Lens Implantation, Intraocular , Lenses, Intraocular/adverse effects , Phacoemulsification/adverse effects , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Prospective Studies , Prosthesis Design , Russia
2.
Bull Exp Biol Med ; 153(1): 5-8, 2012 May.
Article in English | MEDLINE | ID: mdl-22808480

ABSTRACT

We proposed new method for measuring dynamic changes in hunger motivation in rabbits in the course of satisfaction of nutritional need by weight, time, and rate parameters of effective food-procuring behavior. Transformation of the amount of food eaten into the electric signals was performed using electronic weighing machine incorporated into hardware and software system. The most conclusive characteristic for decrease in hunger motivation in the course of first effective food-procuring act was the period of food-procuring cycles, which values increase significantly as animal satisfies its nutritional need, whereas amount of the food consumed for each food-procuring cycle remains constant. Integral characteristics of food-procuring behavior reflect higher level of food motivation in the course of first effective food-procuring act in comparison to the subsequent ones.


Subject(s)
Feeding Behavior/physiology , Hunger/physiology , Motivation/physiology , Animals , Rabbits
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