ABSTRACT
BACKGROUND: Varicella is 25 times more likely to be complicated by pneumonia in adults than in children. Data on changes in lung function following pneumonia are limited. This study was undertaken to describe the epidemiological factors associated with pneumonia and to investigate lung function up to 1 year following chickenpox. METHODS: Thirty eight consecutive suitable patients admitted to a university hospital were enrolled in the study; 19 had pneumonia and 19 did not. Epidemiological data and density of rash were recorded, spirometric tests were performed, and carbon monoxide transfer factor was measured. RESULTS: Varicella pneumonia was associated with the presence of respiratory symptoms (p=0.006), current smoking (p=0.003), and history of close contact (p=0.009). There was a trend towards patients with pneumonia having a more severe rash. No association was observed between pneumonia and age or sex. Current smokers had a higher mean number of spots than non-smokers (p=0.005). Carbon monoxide transfer factor at hospital discharge was reduced in 27 patients (71%), more markedly in the group with pneumonia (p=0.009). Nine patients (seven with pneumonia) still had a reduced carbon monoxide transfer factor (mean reduction 36%) at 12 months. CONCLUSION: Chickenpox may result in a defect in carbon monoxide transfer factor for at least a year after acute illness.
Subject(s)
Chickenpox/complications , Pneumonia, Viral/etiology , Adult , Carbon Dioxide , Chickenpox/physiopathology , Chickenpox/transmission , Female , Follow-Up Studies , Humans , Lung/physiopathology , Male , Odds Ratio , Pneumonia, Viral/physiopathology , Prospective Studies , Pulmonary Gas Exchange , Respiratory Function Tests , Risk Factors , Smoking/adverse effectsABSTRACT
AIMS: The aims of this study were to determine the frequency of needle stick injury (NSI) in general practice, to determine what measures were being taken to protect against needle stick injury, and to gather other information regarding work practices, risk perception, and knowledge of transmission. METHODS: A postal survey was undertaken of all general practitioners and one practice nurse per practice address in selected areas of New Zealand. RESULTS: The response rate was 82%. An incidence rate of 22 needle stick injuries in 100 health care workers per 6 month period was found. For general practitioners alone the incidence rate was 25 in 100 per 6 month period and for practice nurses it was 17 in 100 per 6 month period. Recommended precautionary measures were not being followed by most individuals. CONCLUSIONS: Needle stick injury is a substantial problem in general practice and exposes general practitioners and practice nurses to a serious risk of infection from bloodborne transmissible agents. All patients should be considered to pose a potentially high risk of infection and recommended precautionary measures should be followed at all times.
