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Pharmacokinetics of moxifloxacin in an infant with Mycoplasma hominis meningitis.
Watt, Kevin M; Massaro, Matthew M; Smith, Brian; Cohen-Wolkowiez, Michael; Benjamin, Daniel K; Laughon, Matthew M.
Pediatr Infect Dis J ; 31(2): 197-9, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22016080

ABSTRACT

Treatment of Mycoplasma hominis meningitis in infants is limited by a lack of consensus regarding therapy and limited pharmacokinetic data for agents to which M. hominis is susceptible. We report the successful treatment of a premature infant suffering from M. hominis meningitis with doxycycline and moxifloxacin and provide a pharmacokinetic profile of moxifloxacin.


Subject(s)
Anti-Bacterial Agents/pharmacokinetics , Aza Compounds/pharmacokinetics , Meningitis, Bacterial/drug therapy , Mycoplasma Infections/drug therapy , Mycoplasma hominis/isolation & purification , Quinolines/pharmacokinetics , Adult , Anti-Bacterial Agents/administration & dosage , Aza Compounds/administration & dosage , Child , Child, Preschool , Doxycycline/administration & dosage , Female , Fluoroquinolones , Humans , Infant , Infant, Newborn , Male , Meningitis, Bacterial/microbiology , Moxifloxacin , Mycoplasma Infections/microbiology , Pregnancy , Quinolines/administration & dosage , Treatment Outcome
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