1.
J Org Chem
; 84(9): 5440-5449, 2019 05 03.
Article
in English
| MEDLINE
| ID: mdl-30929443
ABSTRACT
The radical-type ring-opening reaction of gem-difluorocyclopropanes and subsequent regioselective monoepoxidation of the products were demonstrated. Introduction of a vinyl or allyl group to the epoxide produced the diene derivatives that were subjected to the ring closing metathesis reaction to furnish the gem-difluoromethylene containing cyclopentene, cycloheptene, and cyclooctene derivatives in good to excellent yields.
2.
Org Biomol Chem
; 16(33): 6106-6114, 2018 08 22.
Article
in English
| MEDLINE
| ID: mdl-30091778
ABSTRACT
We found that aerobic oxidation took place after the visible light-mediated ring-opening reaction of gem-difluorocyclopropane in the presence of an organic dye and amine to furnish 2,2-difluoro-homoallylic alcohols in good yields.