ABSTRACT
A 53-year-old man had steroid-dependent ulcerative colitis. Leukocytapheresis (LCAP) was carried out to induce remission, but soon hematuria and renal dysfunction appeared. Since he had no autoimmune hemolytic anemia, and there was no possibility of his having had hemolytic uremic syndrome, it was considered that this hemolysis could have been caused by mechanical stimulation on the LCAP column, and then the hemolysate flowed into his body. We should be aware that hematuria might occur as a side effect of LCAP.
Subject(s)
Colitis, Ulcerative/therapy , Hematuria/etiology , Leukapheresis , Renal Insufficiency/etiology , Colitis, Ulcerative/complications , Humans , Male , Middle AgedABSTRACT
A 32-year-old man was admitted to our hospital complaining of abdominal pain in the left upper quadrant. A mass was palpable on the left side of the umbilicus. Laboratory data revealed anemia, elevated erythrocyte sedimentation rate, hypergammaglobulinemia, and prolonged prothrombin time. Computed tomography demonstrated a soft tissue mass in the mesentery of the jejunum, portal venous thrombosis, and cavernomatous transformation in the porta hepatis. The patient was eventually diagnosed by laparoscopic partial resection as having inflammatory pseudotumor of the mesentery. Four months later, all of his symptoms and abnormal laboratory findings completely disappeared without any therapy. Inflammatory pseudotumor should be kept in mind as a cause of portal venous thrombosis, and/or cavernomatous transformation although it is rare.
