ABSTRACT
Typical episodes of apnoea with paleness and cyanosis have been noted noted in premature baby born on the 28th week of pregnancy with body weight 1,010 g as a result of infection with enteropathogenic strain of E. coli O111K58 on the 21st day of life (3rd day of the infection). Effective treatment with antibiotics produced recovery.
Subject(s)
Apnea/etiology , Escherichia coli Infections/complications , Infant, Premature, Diseases , Humans , Infant, Newborn , MaleABSTRACT
Seventy-two newborns at risk of infection were studied. In the afterbirth of these newborns leucocytic infiltrations were found in 31.9% of cases and Gram-positive organisms prevailed. In the group of newborns with leucocytic infiltrations present in the afterbirth, bacteraemia, left-shift of the differential white blood cell count, and decreased platelet count were more frequent. The course of the adaptation period of these newborns was more frequently disturbed, and infections developed more frequently and earlier. The presence of leucocytic infiltrations in the afterbirth of infected newborns points out that the infection developed within the uterus.
Subject(s)
Bacterial Infections/pathology , Placenta/pathology , Bacterial Infections/epidemiology , Female , Humans , Infant, Newborn , Leukocytes , Male , Placenta/microbiology , Pregnancy , Risk FactorsABSTRACT
The studied material comprised 72 newborns at risk of infection. In the afterbirth of these newborns histological examination demonstrated leucocytic infiltrations in 31.9% of cases. In the studied material Gram-positive flora prevailed. In the group of children with the presence of leucocytic infiltrations in the afterbirth bacteremia, left-shift in the differential blood cell count and reduced platelet count were more frequent. The course of the adaptation period was disturbed in a greater number of these babies, and infection became manifest earlier and more frequently. Demonstration of leucocytic infiltrations in the afterbirth of infected newborns is an evidence of intrauterine infection.
Subject(s)
Bacterial Infections/pathology , Placenta/pathology , Bacterial Infections/microbiology , Female , Humans , Infant, Newborn , Leukocytes/physiology , Male , Placenta/microbiology , Pregnancy , RiskABSTRACT
The results of the observation of humoral response in newborns from HBsAg-positive mothers after passive-active or active anti-HBV immunization was presented. Efficacy and safety of this prophylaxis was evaluated. We found similar percentage of anti-HBs response in the all groups of vaccinated children (about 85%).
Subject(s)
Hepatitis B/prevention & control , Immunity, Maternally-Acquired/immunology , Immunization, Passive/methods , Infant, Newborn/immunology , Pregnancy Complications, Infectious/immunology , Vaccines, Synthetic/administration & dosage , Viral Hepatitis Vaccines/administration & dosage , Adolescent , Adult , Female , Hepatitis B/immunology , Hepatitis B Antibodies/analysis , Hepatitis B Antibodies/biosynthesis , Hepatitis B virus/immunology , Humans , Injections, Intramuscular , Injections, Intravenous , Pregnancy , Vaccines, Synthetic/immunology , Viral Hepatitis Vaccines/immunologySubject(s)
Erythrocyte Volume , Infant, Newborn/blood , Blood Viscosity , Capillaries , Female , Hematocrit , Humans , Male , Reference Values , VeinsABSTRACT
A case is reported of icterus of the subcortical ganglia in a premature newborn with total bilirubin level 7.42 mg%. The role of various risk factors in the aetiology of this icterus is discussed.
Subject(s)
Escherichia coli Infections/diagnosis , Infant, Premature, Diseases/etiology , Kernicterus/diagnosis , Bilirubin/blood , Escherichia coli Infections/complications , Humans , Infant, Newborn , Kernicterus/etiology , Male , Risk FactorsABSTRACT
A newborn with Down syndrome (karyotype 47 xy + 21) was observed in whom a transient myeloproliferative reaction occurred, perhaps connected with perinatal infection. The reaction regressed spontaneously. However, the possibility of complete remission cannot be excluded since the proliferative changes may be a preliminary stage of leukaemia.