Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Reprod Toxicol ; 29(3): 353-60, 2010 Jun.
Article in English | MEDLINE | ID: mdl-20096774

ABSTRACT

BACKGROUND: There is a dearth of information on paternal drug exposure at the time of conception. The Motherisk Program, established in 1985, is a teratology information and clinical consultation service on drug safety during pregnancy and lactation, as well as paternal exposure (PEx). Here, we reviewed for the first time our experience with PEx. METHODS: This was an observational retrospective cohort study using a prospectively collected database. Telephone counselling records from January 2002 to December 2007, inclusive, were screened to identify cases concerning PEx. RESULTS: Of a total of 188,188 counselling requests over these 6 years, 301 (0.16%) pertained to PEx. Counselling was most frequently sought on methotrexate, finasteride, prednisone and azathioprine. For many drugs, limited or no information was available on PEx. CONCLUSIONS: Paternal exposure represents a small fraction of counselling requests to Motherisk. Our findings suggest that there is an ongoing need for information on paternal drug exposure.


Subject(s)
Paternal Exposure/adverse effects , Pharmaceutical Preparations , Teratology/statistics & numerical data , Azathioprine/therapeutic use , Breast Feeding/statistics & numerical data , Cohort Studies , Counseling/statistics & numerical data , Databases, Factual , Drug-Related Side Effects and Adverse Reactions , Female , Humans , Lactation/drug effects , Male , Methotrexate/therapeutic use , Pharmaceutical Preparations/classification , Pilot Projects , Pregnancy , Retrospective Studies , Telephone
SELECTION OF CITATIONS
SEARCH DETAIL
...