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1.
Clin Oral Implants Res ; 26(3): 257-62, 2015 Mar.
Article in English | MEDLINE | ID: mdl-25331762

ABSTRACT

AIM: To compare clinical and radiographic outcomes of implants with a Laser-Lok®-microtextured collar to implants with a resorbable blast textured (RBT) collar after a 5-year follow-up period. MATERIALS AND METHODS: Thirty-four implants with a Laser-Lok®-microtextured collar (test group [TG]) and 31 implants with an RBT collar (control group [CG]) were placed in 45 non-smoking, periodontally healthy patients. The full-mouth plaque score, full-mouth bleeding score, number of sites with plaque, and the number of sites with bleeding on probing (BOP) were recorded at baseline, and at 1-, 2-, 3-, 4-, and 5-year follow-up. Probing depth (PD) and mucosal recession were assessed at baseline and after the 5-year follow-up period. The radiographic marginal bone loss (MBL) was calculated by subtracting the bone level at the time of crown insertion from the bone level at the 5-year follow-up. RESULTS: An implant survival rate of 94% and of 90% was reported for the TG and the CG, respectively. No statistical differences were found between the study groups for presence of plaque (10.1% vs. 25%) or for number of sites with BOP (10.3% vs. 23%). The differences between both study groups were statistically significant for mean MBL (0.81 ± 0.24 vs. 2.02 ± 0.32 mm), mean PD (2.32 ± 0.44 vs. 4.25 ± 0.87 mm), and mean mucosal recession (0.16 ± 0.3 vs. 0.22 ± 0.3 mm). CONCLUSIONS: Within the limitations of this study, results suggest that the laser-microtextured implant collar surface may provide more favorable conditions for the attachment of hard and soft tissues, and reduce the level of MBL.


Subject(s)
Alveolar Bone Loss/diagnostic imaging , Dental Implants , Dental Prosthesis Design , Gingival Recession/diagnostic imaging , Lasers , Adult , Crowns , Dental Implantation, Endosseous/methods , Dental Plaque Index , Dental Restoration Failure , Female , Follow-Up Studies , Humans , Male , Middle Aged , Periodontal Index , Retrospective Studies , Surface Properties , Treatment Outcome
2.
Clin Oral Implants Res ; 20(10): 1092-8, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19719737

ABSTRACT

AIM: To assess dimensional ridge alterations following immediate implant placement in molar extraction sites. MATERIAL AND METHODS: Twelve subjects received 12 immediate transmucosal implants in molar extraction sites. Peri-implant defects were treated according to the principles of Guided Bone Regeneration by means of a deproteinized bone substitute and a bioresorbable collagen membrane. Changes in vertical (IS-BD, CREST-BD) and horizontal distances (EC-I, IC-I) of alveolar bony walls to the bottom of the defects (BD) and to the implant surfaces (I) were compared between implant placement and surgical re-entry at 6 months. RESULTS: The implant survival rate at 6 months was 100%. Statistically significant differences (P<0.01) were observed in the mean changes in vertical distances IS-BD and CREST-BD between baseline and re-entry. At re-entry, all peri-implant marginal defects assessed from the internal socket wall to the implant surface (IC-I) were healed. The residual combined thickness of the buccal wall with the newly formed peri-implant bone at sites with an initial thickness of 1 mm was statistically significantly smaller (P<0.05) compared with that of sites with an initial buccal thickness of 2 mm (2.50 +/- 0.76 vs. 4+/-0 mm). CONCLUSIONS: The marginal defects around immediate implants placed in molar extraction sites were completely filled after 6 months of healing through de novo bone formation. Bone resorption was observed from the external aspects of the buccal and oral socket walls. Dimensional changes of the external socket walls were mostly pronounced at the buccal aspects.


Subject(s)
Alveolar Process/physiology , Alveolar Ridge Augmentation/methods , Bone Regeneration/physiology , Dental Implantation, Endosseous/methods , Guided Tissue Regeneration, Periodontal/methods , Tooth Socket/surgery , Adult , Alveolar Bone Loss/prevention & control , Cohort Studies , Crowns , Dental Implantation, Endosseous/adverse effects , Dental Implants, Single-Tooth , Dental Prosthesis, Implant-Supported , Female , Follow-Up Studies , Humans , Male , Middle Aged , Molar/surgery , Osseointegration , Prospective Studies , Time Factors , Tooth Extraction/adverse effects , Treatment Outcome
3.
Clin Oral Implants Res ; 20(5): 482-8, 2009 May.
Article in English | MEDLINE | ID: mdl-19281503

ABSTRACT

AIM: To assess soft tissues healing at immediate transmucosal implants placed into molar extraction sites with buccal self-contained dehiscences. MATERIAL AND METHODS: For this 12-month controlled clinical trial, 15 subjects received immediate transmucosal tapered-effect (TE) implants placed in molar extraction sockets displaying a buccal bone dehiscence (test sites) with a height and a width of > or =3 mm, respectively. Peri-implant marginal defects were treated according to the principles of Guided Bone Regeneration (GBR) by means of deproteinized bovine bone mineral particles in conjunction with a bioresorbable collagen membrane. Fifteen subjects received implants in healed molar sites (control sites) with intact buccal alveolar walls following tooth extraction. In total, 30 TE implants with an endosseous diameter of 4.8 mm and a shoulder diameter of 6.5 mm were used. Flaps were repositioned and sutured, allowing non-submerged, transmucosal soft tissues healing. At the 12-month follow-up, pocket probing depths (PPD) and clinical attachment levels (CAL) were compared between implants placed in the test and the control sites, respectively. RESULTS: All subjects completed the 12-month follow-up period. All implants healed uneventfully, yielding a survival rate of 100%. After 12 months, statistically significantly higher (P<0.05) PPD and CAL values were recorded around implants placed in the test sites compared with those placed in the control sites. CONCLUSIONS: The findings of this controlled clinical trial showed that healing following immediate transmucosal implant installation in molar extraction sites with wide and shallow buccal dehiscences yielded less favorable outcomes compared with those of implants placed in healed sites, and resulted in lack of 'complete' osseointegration.


Subject(s)
Dental Implantation, Endosseous/methods , Dental Implants, Single-Tooth , Osseointegration/physiology , Surgical Wound Dehiscence/complications , Tooth Socket/surgery , Wound Healing/physiology , Adult , Animals , Bone Matrix/transplantation , Cattle , Chi-Square Distribution , Crowns , Dental Prosthesis, Implant-Supported , Dental Restoration Failure , Female , Follow-Up Studies , Guided Tissue Regeneration, Periodontal/methods , Humans , Male , Middle Aged , Minerals/therapeutic use , Molar , Mouth Mucosa/physiology , Osseointegration/drug effects , Periodontal Index , Prospective Studies , Surgical Wound Dehiscence/therapy , Tooth Extraction , Tooth Socket/drug effects , Wound Healing/drug effects
4.
Plast Reconstr Surg ; 108(1): 208-14; discussion 215-7, 2001 Jul.
Article in English | MEDLINE | ID: mdl-11420526

ABSTRACT

Inactivation of the orbicularis oculi muscle by chemodenervation with botulinum toxin type A (Botox, Allergan, Inc., Irvine, Calif.) as a sole procedure or in conjunction with blepharoplasty has proved to be a reliable method to improve the appearance of the periocular area. Botox has the unique and ideal characteristic in that, with repeated use, there is potential for a prolonged clinical effect with smaller dosages. In addition, if a complication does arise--while not aesthetically acceptable and potentially untoward--it is time-limited, and the anatomical area will eventually return to its pretreatment baseline status. In this study, in three cases [in more than 1000 crow's feet treatment sessions (2000 sides)] over the course of 1 year, partial lip ptosis resulting from weakening of the zygomaticus major muscle after the injection of Botox into the periocular region are reported. This article reviews suggested treatment guidelines and anatomic considerations for the periocular region to maintain injection standardization and improve the safety profile of Botox as the aesthetic indications for its use expand and the number of individuals who inject it increases.


Subject(s)
Botulinum Toxins, Type A/adverse effects , Cosmetic Techniques/adverse effects , Facial Muscles/drug effects , Lip , Muscle Weakness/chemically induced , Neuromuscular Agents/adverse effects , Skin Aging , Botulinum Toxins, Type A/administration & dosage , Humans , Injections , Male , Middle Aged , Neuromuscular Agents/administration & dosage , Orbit
5.
J Oral Implantol ; 26(4): 257-61, 2000.
Article in English | MEDLINE | ID: mdl-11831231

ABSTRACT

Bioglass (BG) has been shown recently to be osteoconductive and osteopromotive in different experimental and clinical conditions. The aim of the present study was to evaluate BG particles in bone defects in rabbit tibia. In control sites, bone was observed only in the peripheral areas of the defects, while in test sites, newly formed bone was found around all BG particles, even those located in the central portion of the defect. Osteoblasts were actively secreting osteoid matrix directly on the granules' surface. BG seems to be a highly osteoconductive material.


Subject(s)
Bone Regeneration/drug effects , Bone Substitutes/pharmacology , Ceramics/pharmacology , Animals , Rabbits , Tibia/surgery
6.
Dermatol Clin ; 17(4): 799-804, vi, 1999 Oct.
Article in English | MEDLINE | ID: mdl-10526711

ABSTRACT

Subcutaneous fat deposition on the chest and back is notoriously diet and exercise resistant. The "top heavy" appearance is a source of frustration for patients as well as surgeons. Fortunately, with advent of tumescent liposuction surgery the disparity between the upper and lower torso can now be reconciled.


Subject(s)
Back/surgery , Lipectomy , Thoracic Surgical Procedures/methods , Adipose Tissue/surgery , Adolescent , Adult , Axilla/surgery , Dermatologic Surgical Procedures , Diet , Exercise , Female , Gynecomastia/surgery , Humans , Lipectomy/adverse effects , Lipectomy/methods , Male , Mammaplasty/methods , Middle Aged , Neck/surgery , Thoracic Surgical Procedures/adverse effects
7.
Biomaterials ; 20(5): 485-9, 1999 Mar.
Article in English | MEDLINE | ID: mdl-10204991

ABSTRACT

Twenty-four hollow ITI implants (four screws, and 20 cylinders) were retrieved because of failure, and evaluated in our laboratory, in a eight-year period (1989-1996), to see if a common cause could be observed in this implant design. No selection of these implants was carried out, and they represented the total number of implants of this type received in the above-mentioned time frame. The implants had been inserted by several different clinicians and were received from four universities and a private practice. The implants had been removed for mobility, pain, and presence of a vertical bone loss. About two-thirds of the implants were unstable in the jaw at the time of retrieval. Twenty implants had been used as single implants restoration and four in bridge reconstructions. Most of our specimens showed that the inflammatory process had reached the hollow portion of the implants. The following microscopical features were present in almost all our specimens: calculus and plaque on the coronal portion of the implant surface, presence of proliferating epithelium and of bone sequestra, and presence of bone apically to the inflammatory process. Perhaps, when the inflammatory process reaches the implant hollow portion, the infection runs a more rapid course due to the scarce vascularity of the bone inside this part.


Subject(s)
Dental Implants , Dental Implants, Single-Tooth , Dental Prosthesis Retention , Dental Restoration Failure , Humans , Inflammation/etiology , Inflammation/pathology , Mandible/pathology , Mandible/surgery , Maxilla/pathology , Maxilla/surgery , Prosthesis Design
8.
Plast Reconstr Surg ; 103(2): 645-52; discussion 653-5, 1999 Feb.
Article in English | MEDLINE | ID: mdl-9950556

ABSTRACT

Injections of botulinum A exotoxin are successfully used to treat neuromuscular disorders and to improve hyperkinetic muscles and dynamic rhytids of the upper face. Using these principles, we extended its use to the treatment of the aging neck (hypertrophic platysma muscle bands). A classification system (I to IV) based on horizontal neck rhytids, platysma bands, and skin laxity was devised to categorize the degree of deformity and serve as a guideline for suggested dosages of botulinum. The results correlated with the degree of age-related neck degeneration. Type II (mild horizontal neck rhytids; thin, mild platysma muscle flaccidity; and mild skin laxity) and III (moderate horizontal neck rhytids; thick, moderate platysma muscle flaccidity; and moderate skin laxity) patients were the most satisfied, followed closely by types I and IV. A total of 1500 patients were treated by three independent practices. The majority of them achieved good-to-excellent results, as evaluated by both the physician and patient. The degree of muscle flaccidity and hypertrophy were the factors that most influenced success rates, not the anatomic variations in muscle configuration.


Subject(s)
Botulinum Toxins, Type A/therapeutic use , Neck Muscles , Neuromuscular Agents/therapeutic use , Adult , Aged , Female , Humans , Hypertrophy , Male , Middle Aged , Neck Muscles/pathology , Retrospective Studies , Treatment Outcome
9.
Dermatol Surg ; 24(11): 1249-54, 1998 Nov.
Article in English | MEDLINE | ID: mdl-9834747

ABSTRACT

Clostridium botulinum type A exotoxin is one of the recent advances for treatment of the aging face. Due to the sudden and exponential surge in popularity, there is little precise consensus regarding its safety and efficacy. Many of the reported complications associated with its aesthetic use are few and anecdotal. As we gain more experience and long-term follow-up with this procedure, complications and their treatment can be better documented. As most of the salutary effects of Botulinum toxin are temporary, fortunately, so too are the complications associated with this form of therapy.


Subject(s)
Botulinum Toxins, Type A/adverse effects , Neuromuscular Agents/adverse effects , Contraindications , Facial Muscles/drug effects , Humans , Neck Muscles/drug effects , Oculomotor Muscles/drug effects , Skin Aging/drug effects
11.
Biomaterials ; 19(10): 889-96, 1998 May.
Article in English | MEDLINE | ID: mdl-9690830

ABSTRACT

The aim of this study, in rabbit tibia, was an evaluation of the early reactions of the tissues to the insertion of polylactic membranes, used in connection with titanium implants. The specimens were retrieved after 1-4 weeks, and a histological analysis was performed. It was possible to see that, in the early implantation phases, no degradation of the macrostructure of the membrane was present. On the outer portion of the membrane many multinucleated giant cells (MGC) were present and membrane fragments were present inside the cytoplasm of these cells. These cells could explain the inflammatory processes reported, in some reports, with the use of materials made by polylactic and polyglycolic acid. We did not observe detrimental effects in the bone tissue around the membrane, and the membrane appeared to have a mechanical stability for the time necessary for bone regeneration.


Subject(s)
Lactic Acid/chemistry , Macrophages/immunology , Membranes, Artificial , Polymers/chemistry , Prostheses and Implants , Tibia/chemistry , Animals , Cell Adhesion , Foreign-Body Reaction/immunology , Giant Cells, Foreign-Body , Immunohistochemistry , Male , Polyesters , Rabbits , Tibia/immunology , Titanium
12.
J Periodontol ; 69(2): 185-9, 1998 Feb.
Article in English | MEDLINE | ID: mdl-9526918

ABSTRACT

One of the possible complications of implant treatment is the occurrence of an implant fracture. Metal fatigue and biomechanical overload seem to be the most common causes of fractured implants. This study evaluated 4 implants (3 hollow cylinders and 1 hollow screw) which fractured after a mean loading period of 2.8 years. All implants had a 4 mm diameter and had been inserted in a posterior location. In 3 cases parafunctional habits were present. In all cases a vertical resorption of the peri-implant bone was present. The endosseous portion of the implant presented always a very high bone-implant contact percentage. Scanning electron microscopic examination showed that at least one of the implant holes was involved in the fracture line; no porosities or material defects were observed on the fractured surface of the implant. In hollow implants the holes could represent a site of less resistance.


Subject(s)
Dental Implantation, Endosseous , Dental Implants , Dental Prosthesis Design , Dental Restoration Failure , Alveolar Bone Loss/pathology , Alveolar Process/pathology , Biomechanical Phenomena , Coloring Agents , Dental Occlusion, Traumatic/physiopathology , Evaluation Studies as Topic , Female , Humans , Male , Microscopy, Electron, Scanning , Middle Aged , Osseointegration , Porosity , Stress, Mechanical , Surface Properties , Time Factors
13.
Int J Periodontics Restorative Dent ; 18(5): 444-53, 1998 Oct.
Article in English | MEDLINE | ID: mdl-10093521

ABSTRACT

Twenty buccogingival recessions (3 mm deep) in twenty patients were selected and divided into two groups. Periodontal parameters were recorded (recession reduction, probing depth, clinical attachment level, and keratinized tissue width), and both groups were treated with regenerative therapy using a resorbable polylactic acid membrane. The test group was treated using the double papilla flap procedure, and the control group was treated using the coronally repositioned flap procedure. The results obtained at a 1-year follow-up were comparable between the test and control groups for recession reduction, probing depth, and clinical attachment level, although the test group obtained a very large amount of keratinized gingiva (+74.7%) compared to the control group.


Subject(s)
Gingival Recession/surgery , Guided Tissue Regeneration, Periodontal/methods , Surgical Flaps , Absorbable Implants , Adult , Female , Humans , Lactic Acid , Male , Membranes, Artificial , Polyesters , Polymers , Treatment Outcome
14.
West J Med ; 169(4): 221, 1998 Oct.
Article in English | MEDLINE | ID: mdl-18751117
15.
Dermatol Clin ; 15(4): 569-82, 1997 Oct.
Article in English | MEDLINE | ID: mdl-9348458

ABSTRACT

Cutaneous resurfacing can be accomplished with application of acids, abrasive modalities, or the new generation of carbon dioxide lasers. Ultimately, the universal goal is removal and replacement of the epidermis and dermal collagen remodeling. The indications range from therapeutic and reconstruction to the treatment of the stigmata associated with senescence. The indications are not technique-specific, and the art of cutaneous resurfacing is identifying the cutaneous defect and selecting the appropriate tool or tools to realize the optimal clinical results.


Subject(s)
Chemexfoliation/methods , Dermabrasion/methods , Dermatologic Surgical Procedures , Laser Therapy/methods , Skin Aging , Adult , Aged , Clinical Trials as Topic , Face/surgery , Female , Humans , Male , Middle Aged , Treatment Outcome
16.
Dermatol Surg ; 23(12): 1151-60, 1997 Dec.
Article in English | MEDLINE | ID: mdl-9426659

ABSTRACT

BACKGROUND: Abdominal surgery has evolved from one operation applied to all patients requesting contouring, to a group of procedures based on individual variations in anatomy. Currently, the authors favor four (Types I-IV) different procedures. Liposuction alone (Type I) is performed in the majority of patients. In the remainder (procedures Type II-IV) liposuction combined with modifications of open, traditional abdominoplasty are utilized. These additional methods are appropriate in patients that necessitate rectus muscle reinforcement or skin reduction procedures in order to adequately contour the abdomen. OBJECTIVE: This report describes the indications for abdominal contour surgery, beyond just liposuction. METHODS: A consecutive series of over 300 abdominal contour patients were reviewed and analyzed, with recommendations based on individual variations in their soft tissue anatomy. RESULTS: We demonstrate that the majority of patients benefit from a "closed" procedure (liposuction or ultrasonic assisted liposuction) but that patients with muscle flaccidity or laxity in their skin may require an open procedure. CONCLUSION: Abdominal contour surgery should be considered a group of operations (abdominolipoplasty system of classification and treatment) based on individual varieties in anatomy.


Subject(s)
Abdominal Muscles/surgery , Adipose Tissue/surgery , Lipectomy/methods , Abdominal Muscles/anatomy & histology , Adipose Tissue/anatomy & histology , Adult , Female , Humans , Lipectomy/classification , Male , Middle Aged , Preoperative Care , Terminology as Topic
17.
Biomaterials ; 17(23): 2219-24, 1996 Dec.
Article in English | MEDLINE | ID: mdl-8968515

ABSTRACT

Two cases of non-submerged implants are reported: one was removed, unloaded, after 1 year, for psychiatric reasons, and the other, after a loading period of 4 years, for a fracture of the implant. The implants and surrounding tissues were processed to obtain thin ground sections. In the first case compact lamellar bone was observed in close contact with the titanium all around the implant perimeter. No connective tissue or empty spaces were found at the bone-implant interface. Histochemical staining with von Kossa demonstrated that all the bone around the implant was highly mineralized. No areas of osteoid tissue were found at the bone-implant interface. In the implant retrieved due to fracture it was possible to observe a very high percentage of bone-implant contact.


Subject(s)
Dental Implants , Mandible/pathology , Osseointegration , Titanium , Adsorption , Adult , Humans , Male , Middle Aged , Surface Properties
18.
Semin Cutan Med Surg ; 15(3): 155-61, 1996 Sep.
Article in English | MEDLINE | ID: mdl-8948533

ABSTRACT

Facial skin wrinkling and sagging are concerns that often compel patients to seek counsel on rejuvenative procedures. Facial plasty procedures will alleviate many of these concerns. However, deep chemical peels, in conjunction with surgery or alone, can often significantly improve both the ravages of excess sun exposure and the stigmata of aging.


Subject(s)
Chemexfoliation/methods , Phenols/administration & dosage , Skin Aging/drug effects , Sympatholytics/administration & dosage , Administration, Cutaneous , Combined Modality Therapy , Face/surgery , Female , Follow-Up Studies , Humans , Phenol , Postoperative Care , Surgery, Plastic/methods , Treatment Outcome
19.
J Periodontol ; 67(7): 720-5, 1996 Jul.
Article in English | MEDLINE | ID: mdl-8832484

ABSTRACT

We report on a time course study of cellular colonization of expanded polytetrafluoroethylene (ePTFE) membranes in rabbits. Bone defects (8 mm) were prepared with low speed burs in rabbit tibial metaphyses and covered with ePTFE membranes. The membranes were retrieved after 3, 6, 9, and 12 weeks. At 3 weeks, all membranes were filled by cells and osteoid tissue: no mineralized tissue was found. Osteoblasts positive for alkaline phosphatase (ALP) were observed on the outer surface and inside the material interstices of the membrane. At 6 weeks, it was possible to observe an increase of the quantity of the osteoid material inside the membranes. At 9 weeks, bone tissue was present and it usually originated from the most external part of the membrane, and spread to the central part of the membrane. Only the central portion of this bone appeared to be completely mineralized. A sharp decrease in the number of ALP-positive osteoblasts was observed. At 12 weeks, the quantity of bone present appeared to be substantially increased. Only a small percentage of the bone inside the membrane appeared to be completely mineralized. No cells positive to acid phosphatase were observed. These histological results confirm the high biocompatibility of ePTFE membranes and the bone formation inside the ePTFE interconnected nodes could, probably, help in achieving a good biomaterial-tissue integration with predictable results in bone regeneration.


Subject(s)
Biocompatible Materials , Cell Adhesion/physiology , Membranes, Artificial , Osseointegration/physiology , Osteogenesis/physiology , Polytetrafluoroethylene , Alkaline Phosphatase/analysis , Animals , Guided Tissue Regeneration , Male , Osteoblasts/cytology , Osteoblasts/enzymology , Rabbits
20.
West J Med ; 164(6): 516, 1996 Jun.
Article in English | MEDLINE | ID: mdl-18751042
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