ABSTRACT
OBJECTIVE: To evaluate the effects and safety of topical drops of perfluorohexyloctane (F6H8) on the ocular surface and the corneal endothelium. METHODS: Forty-five patients (90 eyes) diagnosed with dry eye disease were recruited and prescribed treatment with F6H8 as part of a six-month prospective multicentre study. Variables in corneal staining were documented using the National Eye Institute/Industry Workshop scale. The conjunctival variables included using the Oxford scale, as well as corneal parameters, such as central corneal thickness, cell density, coefficient of variation, hexagonality, and mean cell area, at the start of the study, and at 3months and 6months. Compliance and satisfaction with the treatment were measured. RESULTS: F6H8 drops reduced mean corneal staining based on the NEI scale in compliant patients to a mean of -0.84 ± 1.95 at 3months (P=.001) and to -1.65 ± 2.42 at 6months (P<.001). Conjunctival staining at 6months showed a mean decrease of -0.13 (P=.319). The endothelial parameters did not show a significant difference, in contrast to the central corneal thickness that showed a statistically significant decrease (545.30 ± 32.25 at the start of the study to 538.40 ± 31.36 after 6months, P=.009). At the end of the study, 46% of patients reported feeling subjectively better, 40.5% felt the same, and 13.5% felt subjectively worse. CONCLUSIONS: Topical treatment with F6H8 for dried eye disease did not alter the measured variables of the corneal endothelium, but showed improvement in corneal staining and satisfaction.
ABSTRACT
Caso Clínico. Mujer de 45 años que acude a consultas de oftalmología por sensación de cuerpo extraño al parpadeo. A la exploración presenta una tumoración rojiza en la zona superior del canto interno de su ojo derecho. La paciente era tratada por síndrome de ojo seco, con lágrimas artificiales y suero autólogo. Llevaba tres meses con tapones lagrimales de tamaño mediano. Discusión. Destacamos la importancia de una correcta elección del tamaño del tapón lagrimal para disminuir la probabilidad de complicaciones. Presentamos el caso clínico de un granuloma piogénico del punto y canalículo lagrimal, en una portadora de tapones lagrimales (AU)
Case Report. A 45-year-old female was referred to our department due to foreign-body sensation in her right eye. Biomicroscopy examination showed a red ampullary lesion over the right inferior puncta, clinically diagnosed as pyogenic granuloma. This patient, with a longstanding history of dry eyes, had undergone previous treatment with autologous serum eye drops and preservative-free artificial eye drops. Also, for the last three months she was treated with medium size silicone punctal plugs. Discussion. We report a case of a pyogenic granuloma caused by a silicone lagrimal plug. It is important to emphasize the correct choice of plug size and its appropiate placement. Patients with this devices should be informed about possible complications (AU)
Subject(s)
Humans , Female , Middle Aged , Granuloma, Pyogenic/diagnosis , Lacrimal Duct Obstruction/etiology , Xerophthalmia/etiology , Risk Factors , Diagnosis, DifferentialABSTRACT
UNLABELLED: PURPOSE, MATERIAL AND METHOD: Orbitary exenteration is an indicated treatment for malignant and benign processes where special incidence of extension, uncontrollable pain, unrecoverable visual loss, cosmetic disfiguration, tendency to diffuse or persistent infiltration and malignancy potential have been observed. We report a case of a 22 year-old male from Senegal, presenting an isolated neurofibroma of the orbit of long evolution and great size. RESULTS/CONCLUSIONS: Treatment of this tumor is complete local resection. In this case an orbitary exenteration was performed due to size of the tumor and visual loss. We emphasize the need to treat these patients as soon as possible.
Subject(s)
Neurofibroma/surgery , Orbital Neoplasms/surgery , Adult , Exophthalmos/etiology , Eye Enucleation , Humans , Male , Neurofibroma/diagnostic imaging , Orbital Neoplasms/diagnostic imaging , Tomography, X-Ray Computed/methodsABSTRACT
Objetivo/Método: La exenteración orbitaria es un tratamiento indicado en procesos malignos y benignos en los que existan circunstancias especiales de extensión, dolor incontrolable, pérdida irreversible de visión, deformidad, tendencia a infiltración difusa o persistente y posibilidad de malignización.Presentamos el caso de un varón senegalés de 22 años de edad afecto de un neurofibroma solitario de órbita de enormes dimensiones y largo tiempo de evolución.Resultados/Conclusiones: El tratamiento de este tumor es quirúrgico conservador pero en nuestro caso fue preciso realizar una exenteración orbitaria dado su tamaño y pérdida de visión.Destacamos la necesidad de tratar precozmente a estos pacientes (AU)
No disponible
