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1.
Eur J Clin Microbiol Infect Dis ; 41(1): 133-135, 2022 Jan.
Article in English | MEDLINE | ID: mdl-34331601

ABSTRACT

We hereby describe the case of a giant scrotal elephantiasis due to infection by Wuchereria bancrofti, imported in Belgium. We briefly discuss diagnostic methods, their subtlety, and therapeutic possibilities.


Subject(s)
Elephantiasis, Filarial/parasitology , Elephantiasis/parasitology , Scrotum/parasitology , Wuchereria bancrofti/physiology , Aged , Animals , Belgium , Elephantiasis/surgery , Humans , Male , Niger , Scrotum/surgery , Transients and Migrants , Travel , Wuchereria bancrofti/genetics , Wuchereria bancrofti/isolation & purification
2.
J Infect Chemother ; 27(8): 1234-1237, 2021 Aug.
Article in English | MEDLINE | ID: mdl-33589370

ABSTRACT

We present the case of a patient with a voluminous cerebral abscess caused by Aggregatibacter aphrophilus and Actinomyces meyeri occurring a week post dental scaling. Both these bacteria are rarely involved in brain abscesses, and so far, cases of cerebral actinomyces have mostly been treated surgically and with intravenous (IV) antibiotics for 3-4 months, then put on oral antibiotic therapy with penicillin or amoxicillin for a further 3-12 months. Our patient underwent drainage through craniotomy and was subsequently put on intravenous ceftriaxone for 3 months accompanied by brain imaging control at the end of this period which showed complete regression of the abscess. Following parenteral treatment, no oral antibiotics were given since pharmacokinetic properties do not allow to attain high tissue concentration in the brain. This treatment gave excellent results.


Subject(s)
Aggregatibacter aphrophilus , Brain Abscess , Actinomycetaceae , Anti-Bacterial Agents/therapeutic use , Brain Abscess/drug therapy , Ceftriaxone/therapeutic use , Humans
3.
Eur J Trauma Emerg Surg ; 45(4): 681-686, 2019 Aug.
Article in English | MEDLINE | ID: mdl-29855669

ABSTRACT

BACKGROUND: The Trauma-Induced Coagulopathy Clinical Score (TICCS) was developed to be calculable on the site of injury to discriminate between trauma patients with or without the need for damage control resuscitation and thus transfusion. This early alert could then be translated to in-hospital parameters at patient arrival. Base excess (BE) and ultrasound (FAST) are known to be predictive parameters for emergent transfusion. We emphasize that adding these two parameters to the TICCS could improve the scoring system predictability. METHODS: A retrospective study was conducted in the University Hospital of Liège. TICCS was calculated for every patient. BE and FAST results were recorded and points were added to the TICCS according to the TICCS.BE definition (+ 3 points if BE < - 5 and + 3 points in case of a positive FAST). Emergent transfusion was defined as the use of at least one blood product in the resuscitation room. The capacity of the TICCS, the TICCS.BE and the Trauma-Associated Severe Hemorrhage (TASH) to predict emergent transfusion was assessed. RESULTS: A total of 328 patients were included. Among them, 14% needed emergent transfusion. The probability for emergent transfusion grows with the TICCS and the TICCS.BE values. We did not find a significant difference between the TICCS (AUC 0.73) and the TICCS.BE (AUC 0.76). The TASH proved to be more predictive (AUC 0.89). 66.6% of the patients with a TICCS ≥ 10 and 81.5% with a TICCS.BE ≥ 14 required emergent transfusion. CONCLUSION: Adding BE and FAST to the original TICCS does not significantly improve the scoring system predictability. A prehospital TICCS > 10 could be used as a trigger for emergent transfusion activation. TASH could then be used at hospital arrival. Prehospital TASH calculation may be possible but should be further investigated. LEVEL OF EVIDENCE: Diagnostic test, level III.


Subject(s)
Blood Component Transfusion , Emergency Treatment/methods , Hemorrhage/prevention & control , Wounds and Injuries/complications , Adolescent , Adult , Aged , Aged, 80 and over , Belgium , Early Diagnosis , Female , Hemoglobins/analysis , Humans , Injury Severity Score , Male , Middle Aged , Retrospective Studies , Risk Assessment/methods , Young Adult
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