ABSTRACT
Hypertrophic pachymeningitis (HP) is a rare and chronic inflammatory disorder presenting as localized or diffuse thickening of the dura mater. It can be idiopathic or an unusual manifestation of immune-mediated, infectious, and neoplastic conditions. Although some cases may remain asymptomatic, HP can lead to progressive headaches, cranial nerve palsies, hydrocephalus, and other neurological complications, which makes its recognition a fundamental step for prompt treatment. Regarding the diagnosis workup, enhanced MRI is the most useful imaging method to evaluate dural thickening. This article addresses the MR imaging patterns of immune-mediated HP, including immunoglobulin G4-related disease, neurosarcoidosis, granulomatosis with polyangiitis, rheumatoid pachymeningitis, and idiopathic HP. The main infectious and neoplastic mimicking entities are also discussed with reference to conventional and advanced MR sequences.
Subject(s)
Meningitis , Humans , Diagnosis, Differential , Dura Mater/diagnostic imaging , Hypertrophy/diagnostic imaging , Hypertrophy/complications , Magnetic Resonance Imaging , Meningitis/diagnostic imaging , Meningitis/complicationsABSTRACT
Primary intracranial malignant fibrous histiocytoma (MFH), or myxofibrosarcoma, is an extremely rare condition, with only a few cases reported in the literature. We report a case of a dural-based myxofibrosarcoma in a previously healthy 42-year-old man that was initially presumed to be an atypical meningioma. The findings based on conventional and advanced magnetic resonance sequences, including diffusion-weighted imaging, perfusion weighted imaging and proton magnetic resonance spectroscopy, as well as histopathological aspects, are discussed (AU)
El histiocitoma fibroso maligno intracraneal primario (HFM) o mixofibrosarcoma, es una condición extremadamente rara, con solo unos pocos casos reportados en la literatura. Presentamos un caso de mixofibrosarcoma de base dural en un varón de 42 años, previamente sano, que inicialmente se presumió que era un meningioma atípico. Se discuten los hallazgos basados en secuencias de resonancia magnética convencionales y avanzadas, que incluyen imágenes ponderadas por difusión, imágenes ponderadas por perfusión y espectroscopía de resonancia magnética de protones, así como aspectos histopatológicos (AU)
Subject(s)
Humans , Male , Adult , Histiocytoma, Malignant Fibrous/diagnosis , Meningioma/diagnosis , Proton Magnetic Resonance Spectroscopy , Magnetic Resonance Imaging , Diagnosis, DifferentialABSTRACT
Primary intracranial malignant fibrous histiocytoma (MFH), or myxofibrosarcoma, is an extremely rare condition, with only a few cases reported in the literature. We report a case of a dural-based myxofibrosarcoma in a previously healthy 42-year-old man that was initially presumed to be an atypical meningioma. The findings based on conventional and advanced magnetic resonance sequences, including diffusion-weighted imaging, perfusion weighted imaging and proton magnetic resonance spectroscopy, as well as histopathological aspects, are discussed.
Subject(s)
Brain Neoplasms , Histiocytoma, Malignant Fibrous , Meningeal Neoplasms , Meningioma , Adult , Brain Neoplasms/diagnostic imaging , Histiocytoma, Malignant Fibrous/diagnostic imaging , Humans , Magnetic Resonance Imaging/methods , Male , Meningeal Neoplasms/diagnostic imaging , Meningeal Neoplasms/pathology , Meningioma/diagnostic imaging , Meningioma/pathologyABSTRACT
Primary intracranial malignant fibrous histiocytoma (MFH), or myxofibrosarcoma, is an extremely rare condition, with only a few cases reported in the literature. We report a case of a dural-based myxofibrosarcoma in a previously healthy 42-year-old man that was initially presumed to be an atypical meningioma. The findings based on conventional and advanced magnetic resonance sequences, including diffusion-weighted imaging, perfusion weighted imaging and proton magnetic resonance spectroscopy, as well as histopathological aspects, are discussed.
