1.
Gig Sanit
; (7): 55-8, 1982 Jul.
Article
in Russian
| MEDLINE
| ID: mdl-6813196
2.
Biull Eksp Biol Med
; 89(2): 181-2, 1980 Feb.
Article
in Russian
| MEDLINE
| ID: mdl-7370418
ABSTRACT
The effect of xanthine derivatives on platelet aggregation, blood coagulation and the rate of thrombus formation has been studied. Some of the compounds have proved to be effective antiaggregative agents both when added to the platelet enriched plasma and administered to the body.
Subject(s)
Hemostasis/drug effects , Platelet Aggregation/drug effects , Xanthines/pharmacology , Animals , Dose-Response Relationship, Drug , Drug Evaluation, Preclinical , Female , In Vitro Techniques , Male , Platelet Adhesiveness/drug effects , Rabbits , Rats , Thrombosis/drug therapy
3.
Farmakol Toksikol
; 41(4): 405-9, 1978.
Article
in Russian
| MEDLINE
| ID: mdl-668864
ABSTRACT
Tests set up on rats and rabbits showed the ability of phospho-enolpyruvate and pyruvate-kinase to lower the aggregation of thrombocytes and prevent formation of experimental microthrombosis. The joint introduction of these compounds in most experiments resulted in potentiation of the antithrombotic effect.