ABSTRACT
Four hundred children were skin tested with following allergens: Dermatophagoides pteronyssinus, moulds, animal dander (mixture of dog, cat, sheep and horse dander), tree pollens, weed pollen (Ambrosia artemisifolia), and six grass pollens, as well as three nutritive allergens in children less than three years of age. Results demonstrated that in 200 children with perenial rhinitis and/or asthma. Dermatophagoides gave positive results in over 90%. In 200 children with pollen allergy, grasses were major allergens, and among them Timothy (Phleum pratense) gave over 90% of positive results. It is to be concluded than skin testing with many inhalatory allergens is not necessary in patients with typical clinical picture. Skin test with Dermatophagoides and Timothy should be done, and further evaluation taken into consideration only if these are negative.
Subject(s)
Allergens/immunology , Respiratory Hypersensitivity/immunology , Adolescent , Asthma/immunology , Child , Child, Preschool , Female , Humans , Infant , Male , Radioallergosorbent TestABSTRACT
Allergen skin reactivity to histamine assessed by Prick testing was studied in 183 children with different allergic symptoms, aged from 4 months to 15 years. No significant difference was noted in male children versus female in different parts of the arm (antecubital fossa of the left arm, wrist of both arms) and in different allergic disorders (respiratory, pollen and skin allergy). The volume of reaction was not significantly changed in repeated applications of histamine. The peak reaction to histamine appeared 5 minutes after the application of histamine in the majority of children; it gradually declined after 10 and 15 minutes.
