Subject(s)
Myoma/complications , Neoplastic Cells, Circulating/pathology , Uterine Neoplasms/complications , Vena Cava, Inferior/surgery , Venous Thrombosis/etiology , Venous Thrombosis/pathology , Female , Humans , Middle Aged , Myoma/pathology , Uterine Neoplasms/pathology , Vena Cava, Inferior/pathology , Venous Thrombosis/surgerySubject(s)
Pulmonary Embolism , Venous Insufficiency/therapy , Venous Thrombosis , Acute Disease , Chronic Disease , Combined Modality Therapy , Female , Humans , Male , Pulmonary Embolism/drug therapy , Pulmonary Embolism/etiology , Pulmonary Embolism/surgery , Thrombectomy , Ultrasonography , Venous Insufficiency/diagnostic imaging , Venous Thrombosis/complications , Venous Thrombosis/drug therapy , Venous Thrombosis/surgeryABSTRACT
Examination of 64 patients with prior pulmonary artery thromboembolism revealed high blood viscosity in 88% of males and 77% of females. Polycythemia and disturbed erythrocyte deformability were the causes of increased blood viscosity. The degree of disturbed blood viscosity correlated with the degree of hemodynamic disorders. The development of the blood hyperviscosity syndrome was determined by the extent of the affected lungs rather than by the duration of the disease.
Subject(s)
Blood Viscosity , Pulmonary Embolism/blood , Adolescent , Adult , Chronic Disease , Female , Hemodynamics , Humans , Hypertension, Pulmonary/blood , Hypertension, Pulmonary/etiology , Hypertension, Pulmonary/physiopathology , Male , Middle Aged , Pulmonary Embolism/complications , Pulmonary Embolism/physiopathology , Sex Characteristics , SyndromeABSTRACT
Based on studying 34 patients, the authors made a conclusion that transfusion of UVI autoblood improves the pulmonary blood circulation, increases blood oxygenation and deformability of erythrocytes, decreases blood viscosity.
Subject(s)
Blood Transfusion, Autologous/methods , Blood/radiation effects , Hypertension, Pulmonary/therapy , Pulmonary Embolism/complications , Ultraviolet Therapy/methods , Acid-Base Equilibrium , Adolescent , Adult , Blood Gas Analysis , Blood Viscosity , Chronic Disease , Erythrocyte Deformability , Evaluation Studies as Topic , Female , Humans , Hypertension, Pulmonary/blood , Hypertension, Pulmonary/etiology , Male , Middle AgedABSTRACT
Examination of blood rheologic properties in 38 patients with chronic ++post-embolic pulmonary hypertension revealed an elevated blood viscosity at all shift rates and a reduced erythrocyte deformability. A close positive correlation was found between blood viscosity and perfusion deficit. Hemorheologic disorders in patients with chronic post-embolic + pulmonary hypertension are caused by pachyhemia and blood acid-base imbalance due to respiratory failure. They deteriorate pulmonary and systemic hemodynamic disturbances and contribute to progression of blood flow derangement.
Subject(s)
Blood Viscosity/physiology , Erythrocyte Aggregation/physiology , Hypertension, Pulmonary/blood , Pulmonary Embolism/blood , Adult , Chronic Disease , Hematocrit , Humans , Hypertension, Pulmonary/etiology , Middle Aged , Pulmonary Embolism/complicationsABSTRACT
The study examines the potentialities of using radionuclide methods in the diagnosis of cardiac dysfunctions in chronic post-embolic pulmonary hypertension (CPPH). The most informative parameters are shown to be ejection fraction of the right (RV) and left ventricles (LV), severity of RV hypertrophy and dilation, which show changes in relation to the severity of pulmonary hypertension and the disease length. Radiocardiography employed in CPPH has some limitations. Chronic cor pulmonale decompensation due to CPPH is provided by elevated LV contractility. The stage of decompensation is characterized by signs of myocardial dystrophy and impaired perfusion, as judged from 201Tl myocardial scintigraphy, a sharp fall in RV and LV ejection fraction, severe RV myocardial hypertrophy and its cavity dilation.
Subject(s)
Heart/physiopathology , Hypertension, Pulmonary/physiopathology , Pulmonary Embolism/complications , Radionuclide Ventriculography , Adult , Aged , Chronic Disease , Humans , Hypertension, Pulmonary/etiology , Middle Aged , Pulmonary Heart Disease/diagnostic imaging , Pulmonary Heart Disease/etiology , Stroke VolumeABSTRACT
The article is based on study of the immediate results of REPTELA cava-filter implantation in 750 patients and the late-term results in 400 patients. The incidence of the complications is low. Hematoma at the site of subclavian vein puncture developed in 1.6%, retroperitoneal hematomas in 0.1%, migration of the cava-filter occurred in 0.9% of cases. The main causes of the complications are linked with improper methods of implantation of the cava-filter.
Subject(s)
Filtration/instrumentation , Pulmonary Embolism/prevention & control , Vena Cava, Inferior , Follow-Up Studies , Humans , Male , Middle Aged , Pulmonary Embolism/diagnostic imaging , Radiography , Time FactorsABSTRACT
Examination of 38 patients with chronic postembolic pulmonary hypertension revealed gross hemorheological disorders: increased viscosity of blood, extreme aggregation activity of blood cells, diminished property or erythrocytes to undergo deformity when circulating through the capillaries. Small amounts of UV-irradiated autologous blood were infused repeatedly for the correction of these disorders. After a course of treatment the hemorheological indices were normalized in all the patients, which was attended by improvement of the general condition and positive hemodynamic shifts.
Subject(s)
Blood Transfusion, Autologous , Blood Viscosity/radiation effects , Blood/radiation effects , Hypertension, Pulmonary/blood , Pulmonary Embolism/complications , Ultraviolet Therapy , Adult , Chronic Disease , Female , Humans , Hypertension, Pulmonary/etiology , Male , Middle Aged , Pulmonary Embolism/bloodABSTRACT
The work deals with the results of biochemical and angiographic studies in 26 patients with thromboembolism of the pulmonary arteries (TEPA) and pulmonary hypertension of various degree. Acute occlusion of the pulmonary arterial channel calls forth a response of the organism's humoral regulating systems. The degree of hypertension of pulmonary circulation in TEPA, which is determined by the volume of affection of the pulmonary vascular channel, is directly dependent on the functional activity of the adaptation system and the severity of disorders of the intra- and intersystemic connections.
Subject(s)
Neurotransmitter Agents/physiology , Pulmonary Embolism/physiopathology , Adrenal Glands/physiopathology , Humans , Hypertension, Pulmonary/etiology , Hypertension, Pulmonary/physiopathology , Kallikreins/physiology , Kinins/physiology , Pituitary-Adrenal System/physiopathology , Pulmonary Embolism/complications , Renin-Angiotensin System/physiology , Sympathetic Nervous System/physiopathologyABSTRACT
The results of scintigraphy of the right ventricular myocardium with 201T1 and equilibrium ventriculography were described in patients with the acute stage of thromboembolism of the pulmonary artery and chronic post-embolism pulmonary hypertension. A method of quantitative assessment of a degree of right ventricular hypertrophy and dilatation was proposed. Some regularities in the pulmonary heart formation were revealed with regard to a period of disease and the gravity of hemodynamic disturbances in the lesser circulation.
Subject(s)
Heart/diagnostic imaging , Pulmonary Embolism/diagnostic imaging , Pulmonary Heart Disease/diagnostic imaging , Thallium Radioisotopes , Adult , Heart Ventricles/diagnostic imaging , Humans , Middle Aged , Radiography , Radionuclide ImagingABSTRACT
The article discusses the results of biochemical, hemodynamic, and angiographic studies in 33 patients with chronic post-embolic pulmonary hypertension of various degree. The authors show that prolonged occlusion of the pulmono-vascular channel causes predominant activity of the sympathoadrenal, hypophyseal-adrenal, and renin-angiotensin-aldosterone systems, which maintains and aggravates pulmonary hypertension. The degree and character of these changes are directly dependent on the volume of the affection of the pulmonary vascular channel.
Subject(s)
Adaptation, Physiological , Hemodynamics , Hypertension, Pulmonary/physiopathology , Pulmonary Embolism/complications , Adolescent , Adult , Chronic Disease , Female , Humans , Hypertension, Pulmonary/etiology , Male , Middle AgedSubject(s)
Cardiac Complexes, Premature/therapy , Heart Block/therapy , Pacemaker, Artificial , Adolescent , Adult , Aged , Child , Child, Preschool , Female , Humans , Middle Aged , USSRSubject(s)
Pulmonary Embolism/surgery , Adult , Aged , Female , Humans , Male , Middle Aged , Pulmonary Artery/diagnostic imaging , Pulmonary Artery/surgery , RadiographyABSTRACT
The study is based on data of radiopaque investigation of pulmonary vessels in 400 patients with pulmonary arterial thromboembolism. A retrospective assessment of noncontrast chest roentgenograms was carried out in 200 of those. Conventional pulmonary roentgenology was shown to be a fairly unreliable tool of the diagnosis of pulmonary embolism owing to low specificity of the symptoms. Only arterial filling defects and "amputations" may be regarded as specific angiographic signs of thromboembolism. The value of indirect angiographic symptoms was demonstrated. Angiographic semiotics of embolism was studied with reference to the duration of the affection. Vascular filling defects and stenoses are angiographic markers of prolonged presence of thromboemboli in pulmonary arteries.
Subject(s)
Pulmonary Embolism/diagnostic imaging , Angiography , HumansABSTRACT
Radiopaque and radio-isotope findings in the pulmonary arterial channel in 43 patients with postembolic lesions of the pulmonary trunk and its major branches are reported. Angiographic and scanographic symptoms are described. The significance of detected systolic-pressure gradient in the probing of pulmonary vessels is demonstrated. Possible sources of diagnostic errors are analysed, and ways of eliminating them are suggested. Total and selective multipositional angiopulmonography is believed to be the principal method of diagnosing this condition, while pulmonary scanning only allows topical diagnosis in cases of markedly stenosed major pulmonary arteries.