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Phytother Res ; 17(1): 19-25, 2003 Jan.
Article in English | MEDLINE | ID: mdl-12557241

ABSTRACT

The lipoidal matters of Corallina officinalis L. showed a seasonal nonsignificant quantitative variation. However, the fatty acids revealed a relative increase in the summer and winter, while unsaponifiable matter exhibited a slight increase in the spring. The GC/MS analysis of saponifiable and unsaponifiable matter of the algal samples collected in different seasons revealed that samples collected in the spring contained a low cholesterol content and high steroidal compounds as well as high polyunsaturated fatty acids. The alcohol extract, hexane extract and fatty acid fraction of this algal sample exhibited a significant hypolipidaemic activity. Also, two biologically active fractions of hydrocarbons were isolated by CC technique from the hexane fraction of C. officinalis L. and identified by GC/MS.


Subject(s)
Anti-Infective Agents/pharmacology , Fatty Acids/analysis , Hypolipidemic Agents/pharmacology , Lipid Metabolism , Phytotherapy , Plant Extracts/pharmacology , Rhodophyta , Animals , Anti-Bacterial Agents , Anti-Infective Agents/administration & dosage , Cholesterol/metabolism , Cholesterol, HDL/drug effects , Cholesterol, LDL/drug effects , Dose-Response Relationship, Drug , Fungi/drug effects , Gas Chromatography-Mass Spectrometry , Gram-Positive Bacteria/drug effects , Hypolipidemic Agents/administration & dosage , Male , Microbial Sensitivity Tests , Plant Extracts/administration & dosage , Rats , Seasons , Triglycerides/metabolism
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