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1.
Appl Microbiol Biotechnol ; 106(18): 6263-6276, 2022 Sep.
Article in English | MEDLINE | ID: mdl-35972515

ABSTRACT

Peridinin is a light-harvesting carotenoid present in phototrophic dinoflagellates and has great potential for new drug applications and cosmetics development. Herein, the effects of irradiance mediated by light-emitting diodes on growth performance, carotenoid and fatty acid profiles, and antioxidant activity of the endosymbiotic dinoflagellate Durusdinium glynnii were investigated. The results demonstrate that D. glynnii is particularly well adapted to low-light conditions; however, it can be high-light-tolerant. In contrast to other light-harvesting carotenoids, the peridinin accumulation in D. glynnii occurred during high-light exposure. The peridinin to chlorophyll-a ratio varied as a function of irradiance, while the peridinin to total carotenoids ratio remained stable. Under optimal irradiance for growth, there was a peak in docosahexaenoic acid (DHA) bioaccumulation. This study contributes to the understanding of the photoprotective role of peridinin in endosymbiont dinoflagellates and highlights the antioxidant activity of peridinin-rich extracts. KEY POINTS: • Peridinin has a protective role against chlorophyll photo-oxidation • High light conditions induce cellular peridinin accumulation • D. glynnii accumulates high amounts of DHA under optimal light supply.


Subject(s)
Dinoflagellida , Antioxidants , Carotenoids , Chlorophyll , Docosahexaenoic Acids
2.
J Environ Manage ; 320: 115897, 2022 Oct 15.
Article in English | MEDLINE | ID: mdl-35947909

ABSTRACT

The increased demands and dependence on depleted oil reserves, accompanied by global warming and climate change have driven the world to explore and develop new strategies for global sustainable development. Among sustainable biomass sources, microalgae represent a promising alternative to fossil fuel and can contribute to the achievement of important Sustainable Development Goals (SDGs). This article has reviewed the various applications of microalgal biomass that includes (i) the use in aquaculture and its sustainability; (ii) commercial value and emerging extraction strategies of carotenoids; (iii) biofuels from microalgae and their application in internal combustion engines; (iv) the use and reuse of water in microalgae cultivation; and (v) microalgae biotechnology as a key factor to assist SDGs. The future prospects and challenges on the microalgae circular bio economy, issues with regard to the scale-up and water demand in microalgae cultivation are also highlighted.


Subject(s)
Microalgae , Biofuels , Biomass , Sustainable Development , Water
3.
Trends Biotechnol ; 38(1): 1-4, 2020 01.
Article in English | MEDLINE | ID: mdl-31718803

ABSTRACT

Over the past 350 years, Merck has developed science and technology especially in health care, life sciences, and performance materials. To celebrate so many productive years, Merck conducted a special expanded anniversary edition of the Innovation Cup in combination with the scientific conference Curious2018 - Future Insight in Darmstadt, Germany.


Subject(s)
Drug Industry/organization & administration , Synthetic Biology , Awards and Prizes , Humans
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