ABSTRACT
We report a case of a blue-black nodule on the left upper eyelid of a 77-year-old woman. Dermoscopic examination of the lesion revealed a purple or purple-red homogenous opaque area like that often observed in apocrine gland cysts and a yellow-whitish homogenous structure with arborizing vessels. After resection of the tumor, a final diagnosis of collision of an apocrine gland cyst and a trichoblastoma was made. We should note the possibility that trichoblastoma may exhibit a yellow-whitish homogenous structure in dermoscopy.
Subject(s)
Apocrine Glands/pathology , Dermoscopy/methods , Epidermal Cyst/diagnosis , Skin Neoplasms/diagnosis , Sweat Gland Neoplasms/diagnosis , Aged , Diagnosis, Differential , Eyelids , Female , HumansSubject(s)
Carcinoma, Basal Cell/diagnostic imaging , Dermoscopy , Neoplasms, Multiple Primary/diagnostic imaging , Nevus, Pigmented/diagnostic imaging , Nose Neoplasms/diagnostic imaging , Skin Neoplasms/diagnostic imaging , Biomarkers, Tumor/metabolism , Carcinoma, Basal Cell/pathology , Carcinoma, Basal Cell/surgery , Dermis/pathology , Female , Humans , MART-1 Antigen/metabolism , Middle Aged , Neoplasms, Multiple Primary/pathology , Neoplasms, Multiple Primary/surgery , Nevus, Pigmented/pathology , Nevus, Pigmented/surgery , Nose Neoplasms/pathology , Nose Neoplasms/surgery , Skin Neoplasms/pathology , Skin Neoplasms/surgerySubject(s)
Carcinoma/diagnosis , Cicatrix, Hypertrophic/diagnosis , Keloid/diagnosis , Rare Diseases/diagnosis , Sweat Gland Neoplasms/diagnosis , Biopsy , Carcinoma/pathology , Carcinoma/surgery , Diagnosis, Differential , Hand , Humans , Immunohistochemistry , Male , Middle Aged , Rare Diseases/pathology , Sweat Gland Neoplasms/pathology , Sweat Gland Neoplasms/surgery , SyringomaSubject(s)
Carcinoma, Skin Appendage/diagnosis , Dermoscopy/methods , Skin Neoplasms/diagnosis , Sweat Gland Neoplasms/diagnosis , Biopsy, Needle , Carcinoma, Skin Appendage/pathology , Carcinoma, Skin Appendage/surgery , Cheek/pathology , Diagnosis, Differential , Female , Humans , Immunohistochemistry , Middle Aged , Skin Neoplasms/pathology , Skin Neoplasms/surgery , Sweat Gland Neoplasms/pathology , Sweat Gland Neoplasms/surgery , Treatment OutcomeABSTRACT
BACKGROUND: The removal of unwanted body fat using a noninvasive technique is desirable to patients and physicians. The authors describe a controlled, multicenter, clinical trial assessing the safety and efficacy of a focused therapeutic ultrasound device for noninvasive body contouring. METHODS: Eligible healthy adult subjects were enrolled to the experimental group or the control group at five sites. The experimental group received one treatment with the Contour I device (UltraShape Ltd., Tel Aviv, Israel) in the abdomen, thighs, or flanks and were evaluated over a 12-week period. Efficacy outcomes were reduction of circumference and fat thickness. Circumference reduction was compared with the untreated group and with an untreated area (thigh) within the treated group. Safety monitoring included laboratory testing (including serum lipids), pulse oximetry, and liver ultrasound. RESULTS: One hundred sixty-four subjects participated in the study (137 subjects in the experimental group and 27 in the control, untreated group). A single Contour I treatment was safe and well tolerated and produced a mean reduction of approximately 2 cm in treatment area circumference and approximately 2.9 mm in skin fat thickness. The majority of the effect was achieved within 2 weeks and was sustained at 12 weeks. No clinically significant changes in the measured safety parameters were recorded. Seven adverse events were reported, all of which were anticipated, mild, and resolved within the study period. CONCLUSION: The Contour I device provides a safe and effective noninvasive technology for body contouring.
