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2.
Cochrane Database Syst Rev ; 10: CD007429, 2019 10 11.
Article in English | MEDLINE | ID: mdl-31604007

ABSTRACT

BACKGROUND: Dislocation of the acromioclavicular joint is one of the most common shoulder injuries in a sport-active population. The question of whether surgery should be used remains controversial. This is an update of a Cochrane Review first published in 2010. OBJECTIVES: To assess the effects (benefits and harms) of surgical versus conservative (non-surgical) interventions for treating acromioclavicular dislocations in adults. SEARCH METHODS: We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (to June 2019), the Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library 2019, Issue 6), MEDLINE (1946 to June 2019), Embase (1980 to June 2019), and LILACS (1982 to June 2019), trial registries, and reference lists of articles. There were no restrictions based on language or publication status. SELECTION CRITERIA: We included all randomised and quasi-randomised trials that compared surgical with conservative treatment of acromioclavicular dislocation in adults. DATA COLLECTION AND ANALYSIS: At least two review authors independently performed study screening and selection, 'Risk of bias' assessment, and data extraction. We pooled data where appropriate and used GRADE to assess the quality of evidence for each outcome. MAIN RESULTS: We included five randomised trials and one quasi-randomised trial. The included trials involved 357 mainly young adults, the majority of whom were male, with acute acromioclavicular dislocation. The strength of the findings in all studies was limited due to design features, invariably lack of blinding, that carry a high risk of bias. Fixation of the acromioclavicular joint using hook plates, tunnelled suspension devices, coracoclavicular screws, acromioclavicular pins, or (usually threaded) wires was compared with supporting the arm in a sling or similar device. After surgery, the arm was also supported in a sling or similar device in all trials. Where described in the trials, both groups had exercise-based rehabilitation. We downgraded the evidence for all outcomes at least two levels, invariably for serious risk of bias and serious imprecision.Low-quality evidence from two studies showed no evidence of a difference between groups in shoulder function at one year, assessed using the Disability of the Arm, Shoulder, and Hand questionnaire (DASH) (0 (best function) to 100 (worst function)): mean difference (MD) 0.73 points, 95% confidence interval (CI) -2.70 to 4.16; 112 participants. These results were consistent with other measures of function at one-year or longer follow-up, including non-validated outcome scores reported by three studies. There is low-quality evidence that function at six weeks may be better after conservative treatment, indicating an earlier recovery. Very low-quality evidence from one trial found no difference between groups in participants reporting pain at one year: risk ratio (RR) 1.32, 95% CI 0.54 to 3.19; 79 participants. There is very low-quality evidence that surgery may not reduce the risk of treatment failure, usually resulting in non-routine secondary surgery: 14/168 versus 15/174; RR 0.99, 95% CI 0.51 to 1.94; 342 participants, 6 studies. The main source of treatment failure was complications related to surgical implants in the surgery group and persistent symptoms, mainly discomfort, due to the acromioclavicular dislocation in the conservatively treated group.There is low-quality evidence from two studies that there may be little or no difference between groups in the return to former activities (sports or work) at one year: 57/67 versus 62/70; RR 0.96, 95% CI 0.85 to 1.10; 137 participants, 2 studies. Low-quality but consistent evidence from four studies indicated an earlier recovery in conservatively treated participants compared with those treated with surgery. There is low-quality evidence of no clinically important difference between groups at one year in quality of life scores, measured using the 36-item or 12-item Short Form Health Survey (SF-36 or SF-12) (0-to-100 scale, where 100 is best score), in either the physical component (MD -0.63, 95% CI -2.63 to 1.37; 122 participants, 2 studies) or mental component (MD 0.47 points, 95% CI -1.51 to 2.44; 122 participants). There is very low-quality and clinically heterogenous evidence of a greater risk of an adverse event after surgery: 45/168 versus 16/174; RR 2.82, 95% CI 1.65 to 4.82; 342 participants, 6 studies; I2 = 48%. Common adverse outcomes were hardware complications or discomfort (18.5%) and infection (8.7%) in the surgery group and persistent symptoms (7.1%), mainly discomfort, in the conservatively treated group. The majority of surgical complications occurred in older studies testing now-outdated devices known for their high risk of complications. The very low-quality evidence from one study (70 participants) means that we are uncertain whether there is a between-group difference in patient dissatisfaction with cosmetic results.It is notable that the evidence for function, return to former activities, and quality of life came from the two most recently conducted studies, which tested currently used devices and interventions in clearly defined participant populations that represented the commonly perceived population for which there is uncertainty over the use of surgery. There were insufficient data to conduct subgroup analysis relating to type of injury and whether surgery involved ligament reconstruction or not. AUTHORS' CONCLUSIONS: There is low-quality evidence that surgical treatment has no additional benefits in terms of function, return to former activities, and quality of life at one year compared with conservative treatment. There is, however, low-quality evidence that people treated conservatively had improved function at six weeks compared with surgical management. There is very low-quality evidence of little difference between the two treatments in pain at one year, treatment failure usually resulting in secondary surgery, or patient satisfaction with cosmetic result. Although surgery may result in more people sustaining adverse events, this varied between the trials, being more common in techniques such as K-wire fixation that are rarely used today. There remains a need to consider the balance of risks between the individual outcomes: for example, surgical adverse events, including wound infection or dehiscence and hardware complication, against risk of adverse events that may be more commonly associated with conservative treatment such as persistent symptoms or discomfort, or both.There is a need for sufficiently powered, good-quality, well-reported randomised trials of currently used surgical interventions versus conservative treatment for well-defined injuries.

3.
Conserv Biol ; 28(2): 580-93, 2014 Apr.
Article in English | MEDLINE | ID: mdl-24372997

ABSTRACT

A major question in global environmental policy is whether schemes to reduce carbon pollution through forest management, such as Reducing Emissions from Deforestation and Degradation (REDD+), can also benefit biodiversity conservation in tropical countries. We identified municipalities in Brazil that are priorities for reducing rates of deforestation and thus preserving carbon stocks that are also conservation targets for the endangered jaguar (Panthera onca) and biodiversity in general. Preliminary statistical analysis showed that municipalities with high biodiversity were positively associated with high forest carbon stocks. We used a multicriteria decision analysis to identify municipalities that offered the best opportunities for the conservation of forest carbon stocks and biodiversity conservation under a range of scenarios with different rates of deforestation and carbon values. We further categorized these areas by their representativeness of the entire country (through measures such as percent forest cover) and an indirect measure of cost (number of municipalities). The municipalities that offered optimal co-benefits for forest carbon stocks and conservation were termed REDDspots (n = 159), and their spatial distribution was compared with the distribution of current and proposed REDD projects (n = 135). We defined REDDspots as the municipalities that offer the best opportunities for co-benefits between the conservation of forest carbon stocks, jaguars, and other wildlife. These areas coincided in 25% (n = 40) of municipalities. We identified a further 95 municipalities that may have the greatest potential to develop additional REDD+ projects while also targeting biodiversity conservation. We concluded that REDD+ strategies could be an efficient tool for biodiversity conservation in key locations, especially in Amazonian and Atlantic Forest biomes.


Subject(s)
Biodiversity , Carbon/analysis , Conservation of Natural Resources , Panthera/physiology , Animals , Brazil , Ecosystem , Forestry
4.
Trials ; 14: 246, 2013 Aug 07.
Article in English | MEDLINE | ID: mdl-23924198

ABSTRACT

BACKGROUND: Humeral shaft fractures account for 1 to 3% of all fractures in adults and for 20% of all humeral fractures. Non-operative treatment is still the standard treatment of isolated humeral shaft fractures, although this method can present unsatisfactory results. Surgical treatment is reserved for specific conditions. Modern concepts of internal fixation of long bone shaft fractures advocate relative stabilisation techniques with no harm to fracture zone. Recently described, minimally invasive bridge plate osteosynthesis has been shown to be a secure technique with good results for treating humeral shaft fractures. There is no good quality evidence advocating which method is more effective. This randomised controlled trial will be performed to investigate the effectiveness of surgical treatment of humeral shaft fractures with bridge plating in comparison with conservative treatment with functional brace. METHODS/DESIGN: This randomised clinical trial aims to include 110 patients with humeral shaft fractures who will be allocated after randomisation to one of the two groups: bridge plate or functional brace. Surgical treatment will be performed according to technique described by Livani and Belangero using a narrow DCP plate. Non-operative management will consist of a functional brace for 6 weeks or until fracture consolidation. All patients will be included in the same rehabilitation program and will be followed up for 1 year after intervention. The primary outcome will be the DASH score after 6 months of intervention. As secondary outcomes, we will assess SF-36 questionnaire, treatment complications, Constant score, pain (Visual Analogue Scale) and radiographs. DISCUSSION: According to current evidence shown in a recent systematic review, this study is one of the first randomised controlled trials designed to compare two methods to treat humeral shaft fractures (functional brace and bridge plate surgery).


Subject(s)
Bone Plates , Braces , Fracture Fixation, Internal/instrumentation , Humeral Fractures/surgery , Osseointegration , Research Design , Brazil , Clinical Protocols , Equipment Design , Fracture Fixation, Internal/adverse effects , Fracture Fixation, Internal/rehabilitation , Fracture Healing , Humans , Humeral Fractures/diagnosis , Pain Measurement , Predictive Value of Tests , Prosthesis Design , Surveys and Questionnaires , Time Factors , Treatment Outcome
5.
BMC Musculoskelet Disord ; 10: 120, 2009 Oct 01.
Article in English | MEDLINE | ID: mdl-19793401

ABSTRACT

BACKGROUND: Fractures of the proximal radius need to be classified in an appropriate and reproducible manner. The aim of this study was to assess the reliability of the three most widely used classification systems. METHODS: Elbow radiographs images of patients with proximal radius fractures were classified according to Mason, Morrey, and Arbeitsgemeinschaft für osteosynthesefragen/Association for the Study of Internal Fixation (AO/ASIF) classifications by four observers with different experience with this subject to assess their intra- and inter-observer agreement. Each observer analyzed the images on three different occasions on a computer with numerical sequence randomly altered. RESULTS: We found that intra-observer agreement of Mason and Morrey classifications were satisfactory (kappa = 0.582 and 0.554, respectively), while the AO/ASIF classification had poor intra-observer agreement (kappa = 0.483). Inter-observer agreement was higher in the Mason (kappa = 0.429-0.560) and Morrey (kappa = 0.319-0.487) classifications than in the AO/ASIF classification (kappa = 0.250-0.478), which showed poor reliability. CONCLUSION: Inter- and intra-observer agreement of the Mason and Morey classifications showed overall satisfactory reliability when compared to the AO/ASIF system. The Mason classification is the most reliable system.


Subject(s)
Radius Fractures/classification , Radius Fractures/diagnostic imaging , Humans , Radiography , Reproducibility of Results
6.
Rev. bras. ortop ; 39(11/12): 679-684, nov.-dez.2004. tab
Article in Portuguese | LILACS | ID: lil-403009

ABSTRACT

Os autores relatam a experiência obtida no Setor de Ombro e Cotovelo (SOC) da Unifesp/EPM em 769 cirurgias realizadas ambulatorialmente, no período de janeiro de 2000 a dezembro de 2003. Apresentam resultados e discutem indicações, critérios de seleção dos pacientes, posição dos anestesiologistas e vantagens dos procedimentos cirúrgicos sem internação. O objetivo do trabalho foi demonstrar que certas cirurgias no ombro e cotovelo podem ser realizadas em regime ambulatorial, sem risco adicional para o paciente, reduzindo o tempo de internação e o custo do procedimento


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Ambulatory Surgical Procedures , Elbow , Shoulder
7.
Arthroscopy ; 20(8): e109-11, 2004 Oct.
Article in English | MEDLINE | ID: mdl-15483533

ABSTRACT

The authors describe arthroscopic reduction and percutaneous fixation of greater tuberosity fractures of the humerus with displacement of more than 0.5 cm. Arthroscopy for reduction and fixation of this fracture presents the same difficulties and advantages as arthroscopic repair of rotator cuff tears.


Subject(s)
Fracture Fixation, Internal/methods , Humeral Fractures/surgery , Shoulder Fractures/surgery , Humans
8.
Rev. bras. ortop ; 29(9): 685-8, set. 1994. ilus
Article in Portuguese | LILACS | ID: lil-199703

ABSTRACT

Calcinose tumoral, descrita inicialmente por Inclan, é uma patologia rara de etiologia indeterminada, caracterizada pela formaçäo de grande massas calcificadas em regiöes justarticulares, geralmente em pontos de pressäo. Os aspectos radiográfico e histológico säo bastante característicos. Os autores relatam quatro casos de calcinose tumoral localizados em punhos e mäos.


Subject(s)
Humans , Female , Adult , Middle Aged , Calcinosis/surgery , Monoamine Oxidase/pathology , Wrist/pathology , Calcinosis/diagnosis , Calcinosis/pathology
9.
Rev. bras. ortop ; 29(4): 211-7, abr. 1994. ilus, tab
Article in Portuguese | LILACS | ID: lil-203421

ABSTRACT

Os autores estudaram experimentalmente cinco modelos de osteossíntese, [1) placas e parfusos; 2) duas cerclagens intra-ósseas perpendiculares; 3) dois fios de Kirschner associados à cerclagem em oito; 4) dois fios de Kirschner cruzados; 5) dois fios de Kirschner associados à cerclagem externa] e um grupo controle (6), realizadas em metacarpianos humanos secos submetidos à força de flexäo. Concluíram que o tipo de ostessíntese mais rígida foi o do grupo 1 (placas e parafusos dorsais) e que o grupo 4 (dois fios de Kirschner cruzados) foi o que teve o pior desempenho global.


Subject(s)
Humans , Fracture Fixation, Internal/methods , Metacarpus/surgery , Cadaver , Metacarpus/injuries , Tensile Strength
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