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1.
Chem Commun (Camb) ; 47(20): 5822-4, 2011 May 28.
Article in English | MEDLINE | ID: mdl-21487614

ABSTRACT

An efficient route to a variety of 2-phenylindolin-3-ones from amino acid methyl esters has been developed. The reaction of amino acid methyl esters with benzyne prepared from 2-(trimethylsilyl)phenyl triflate and CsF gave 2-phenylindolin-3-ones in moderate to good yields.


Subject(s)
Amino Acids/chemistry , Crystallography, X-Ray , Esters , Indoles/chemistry , Molecular Conformation
2.
Org Lett ; 11(1): 169-71, 2009 Jan 01.
Article in English | MEDLINE | ID: mdl-19053733

ABSTRACT

The reaction of salicylaldehydes with benzyne prepared from o-trimethylsilyphenyl triflate and CsF gave xanthenes and xanthones. When the reaction was carried out under basic conditions, 9-hydroxyxanthenes (xanthols) were obtained in good yields.


Subject(s)
Aldehydes/chemistry , Benzene Derivatives/chemistry , Xanthenes/chemical synthesis , Xanthones/chemical synthesis , Molecular Structure , Stereoisomerism , Xanthenes/chemistry , Xanthones/chemistry
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