[Placement of stent for internal carotid artery stenosis in the cervical portion improved ocular ischemic syndrome].

We report a case of ocular ischemic syndrome due to severe stenosis of the internal carotid artery. The patient was a 67-year-old man with a hemispheric transient ischemic attack and an amaurosis fugax. Ocular examination showed multiple soft exudates and dilatation of the retinal veins. Carotid stenting was performed to reconstruct the internal carotid artery. The multiple soft exudates were almost diminished and the visual acuity was improved. These results suggest that carotid stenting for severe stenosis of the internal carotid artery should be one of the less invasive methods to improve the microcirculation of the retina.

Mesectodermal leiomyoma of the ciliary body. An ultrastructural study.

Electron microscopic observation of a mesectodermal leiomyoma of the ciliary body, in which clear perinuclear halos were present, revealed the ultrastructural characteristics of smooth muscle cells, which include myofilaments with fusiform densities, dense attachments, external lamina, and pinocytotic vesicles. In addition, fibrillary cytoplasmic processes containing large numbers of myofilaments with fusiform densities were notably arranged in a neurogenic pattern when observed under a light microscope. These are characteristic of and specific to mesectodermal leiomyomas. Masses or cords of large, polygonal cells with clear halos surrounding the large, round-to-oval nuclei were found to contain only a few myofilaments. Such features are atypical of mesectodermal leiomyomas. Melanocytes were scattered throughout the tumor, providing additional evidence for the neural crest theory of origination of mesectodermal leiomyomas, since melanocytes are well-recognized descendants of the neural crest. A small number of lipid droplets, abundant lysosomes, and, occasionally, phagosomes were also observed in the cells of this mesectodermal leiomyoma.

[Studies on fortimicin in the field of ophthalmology].

Bacteriological and clinical studies of fortimicin in the field of ophthalmology were performed and the results obtained were as follows. 1. The concentration of fortimicin in serum, primary aqueous humor and secondary aqueous humor after intramuscular injection of 30 mg/kg to rabbit reached the peak value of 23.36 microgram/ml after 1/2 hour, 6.07 microgram/ml after 1 hour and 60.6 microgram/ml after 1 hour, respectively. 2. The concentration of fortimicin in primary aqueous humor after subconjunctival injection of 10 mg (0.5 ml) in the rabbit eye reached the peak value of 8.06 microgram/ml after 1/2 hour. 3. The concentration of fortimicin in plasma and primary aqueous humor after intramuscular injection of 200 mg in patients of cataract before operation reached the value of 8.85 microgram/ml and 0.74 microgram/ml after 1 hour. 4. Fortimicin was administered to 5 cases of internal hordeolum and 2 cases of corneal ulcer. Clinical effects were excellent in 3 cases, good in 2 cases and fair in 2 cases. Side effect was observed diarrhea, but the causal relationship with fortimicin was unknown.