ABSTRACT
This work aimed to evaluate the effects of whey protein concentrate (WPC) admixtured of curcumin on metabolic control, inflammation and oxidative stress in Wistar rats submitted to exhaustive exercise. A total of forty-eight male rats were divided into six experimental groups (n 8): standard diet group (AIN-93M), standard diet submitted to exhaustion test group (AIN-93M ET), WPC admixtured of curcumin group (WPC + CCM), WPC + CCM submitted to exhaustion test group (WPC + CCM ET), CCM group and CCM subjected to exhaustion test group (CCM ET). The swimming exhaustion test was performed after 4 weeks of experiment. The consumption of WPC + CCM as well as isolated CCM did not alter the biometric measurements, the animals' food consumption and the hepatic and kidney function, as well as the protein balance of the animals (P > 0·05), but reduced the glycaemia and the gene expression of TNF-α and IL-6 and increased the expression of IL-10 (P < 0·05). The animals that were submitted to the exhaustion test (AIN-93M ET) showed higher aspartate aminotransferase values when compared to the animals that did not perform the exercise (AIN-93 M) (P < 0·05). WPC + CCM reduced the concentration of nitric oxide, carbonylated protein and increased the concentration of catalase (P < 0·05). Both (WPC + CCM and CCM) were able to increase the concentrations of superoxide dismutase (P < 0·05). We concluded that the WPC admixtured of CCM represents a strategy capable of decreasing blood glucose and oxidative and inflammatory damage caused by exhaustive physical exercise in swimming.
Subject(s)
Curcumin , Animals , Curcumin/pharmacology , Inflammation/prevention & control , Male , Oxidative Stress , Rats , Rats, Wistar , Whey Proteins/pharmacologyABSTRACT
Studies evaluating the quality of food providers and the guidelines for their better qualification are scarce in literature. A structured checklist was applied in the supplier establishments to evaluate: infrastructure, sanitary-hygiene control of foods and handlers, and conditions of transportation and receiving. The Supplier Quality Index was used to calculate the scores of vendors, and the score was assigned according to the fulfillment of the items presented on the checklist: "compliant", >75.0 percent compliance and "non compliant", ≥75.0 percent. The items "control of food hygiene and sanitary" and "infrastructure" showed the highest rate of compliance (85.15 percent, each), while the "sanitary-hygiene control of handlers" was that of most frequent non-compliance (80.0 percent). The proposed methodology was efficient and may serve as a model to be employed for evaluation of supplier performance.
Pocos estudios evalúan la calidad de los proveedores de materia prima y los guían para que cumplan mejor los requisitos. En este trabajo se utilizó una lista de verificación en los establecimientos de los proveedores para evaluar: infraestructura, control sanitario de los alimentos y manipuladores, así como las condiciones de transporte y recepción de la material prima. Se utilizó el Índice de Calidad del Proveedor para calcular las puntuaciones, y la clasificación fue asignada de acuerdo con el cumplimiento de los ítems que figuran en la lista de verificación: "conforme" ≥75,0 por ciento y "no conforme" <75,0 por ciento de cumplimiento. El ítem "control higiénico de los manipuladores" tuvo la mayor frecuencia de incumplimiento (80 por ciento), mientras que los ítens "control higiénico del alimento" y "infraestructura" mostraron el más alto índice de cumplimiento (85,15 por ciento, cada). La metodología propuesta fue eficiente, y puede servir como modelo a ser utilizado para la evaluación de los proveedores.
