The association between 24-hour ambulatory blood pressure measurement and selected biochemical and anthropometric parameters in women with polycystic ovary syndrome.

OBJECTIVE: Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorders, which may contribute to the development of cardiovascular diseases. The aim of our study was to evaluate the association between of 24-hour ambulatory blood pressure measurement (ABPM) and selected biochemical and anthropometric parameters in women with PCOS. PATIENTS AND METHODS: The study involved 153 Polish, Caucasian women with PCOS hospitalized in the Department of Endocrinology Gynecology from January 2018 to March 2020. All women had stable body mass during the 3-month period. ABPM was performed using a portable lightweight device with oscillometric technology accepted by International Protocol of European Society of Hypertension (ABPM, HolCARD CR-07, Poland). RESULTS: The first factor taken into consideration was the variability phenotypic subgroups of PCOS on the values of 24-hour ABPM. We revealed that the daytime and night-time systolic and diastolic blood pressure values were significantly higher in phenotype A subgroup than in other subgroups. Moreover, daytime and night-time systolic and diastolic blood pressure value as well as day-time heart ratio value were significantly higher in subgroup with than without hyperandrogenemia. The obese women with PCOS were characterized of the highest value of all night-time measurements among women with PCOS and normal weight, overweight or obesity. In addition, insulin resistance in the PCOS subgroup was associated with lower value of systolic, diastolic blood pressure and both at daytime and night-time heart rate value than in insulin sensitive PCOS subgroup. CONCLUSIONS: Hyperandrogenemia and obesity were the crucial influencing factors on 24-hour ABPM in the group of women with PCOS. In addition, hypertension, apart from visceral obesity, hyperinsulinemia and insulin resistance, could be considered as component of metabolic syndrome in women with PCOS.

Radiologic measurement of cochlea and hearing preservation rate using slim straight electrode (CI422) and round window approach.

Hearing preservation surgery constitutes a considerable branch of cochlear implantation surgery and is being steadily developed and perfected. The aim of the study was to verify if insertion of a cochlear implant electrode according to individually calculated linear insertion depth improves hearing preservation. We evaluated the relations between the size of a cochlea, insertion depth angle, linear insertion depth and hearing preservation rate (HP) according to Hearing Preservation Classification in a retrospective case review of 54 patients implanted with a slim straight electrode Nucleus CI422 in 2008-2011. Group HP was 0.75 at activation, 0.67 at 12 months (for 53 patients) and 0.60 at 24 months. In 53 cases, the mean insertion depth angle was 375° (SD 17°); mean calculated cochlear duct length 35.87 mm (SD 1.95); mean calculated linear insertion depth 23.14 mm (SD 1.68). There was no significantly relevant relation between HP values and angular insertion depth or insertion depth. Preoperative measurements of cochlea and specific parameters such as linear insertion depth have no effect on hearing preservation. Poor hearing preservation in some deep insertion cases cannot be explained entirely by the electrode position.

Pseudogap phase of cuprate superconductors confined by Fermi surface topology.

The properties of cuprate high-temperature superconductors are largely shaped by competing phases whose nature is often a mystery. Chiefly among them is the pseudogap phase, which sets in at a doping p* that is material-dependent. What determines p* is currently an open question. Here we show that the pseudogap cannot open on an electron-like Fermi surface, and can only exist below the doping p FS at which the large Fermi surface goes from hole-like to electron-like, so that p* ≤ p FS. We derive this result from high-magnetic-field transport measurements in La1.6-x Nd0.4Sr x CuO4 under pressure, which reveal a large and unexpected shift of p* with pressure, driven by a corresponding shift in p FS. This necessary condition for pseudogap formation, imposed by details of the Fermi surface, is a strong constraint for theories of the pseudogap phase. Our finding that p* can be tuned with a modest pressure opens a new route for experimental studies of the pseudogap.

Preservation of cochlear structures and hearing when using the Nucleus Slim Straight (CI422) electrode in children.

OBJECTIVE: In cochlear implantation, there are two crucial factors promoting hearing preservation: an atraumatic surgical approach and selection of an electrode that does not damage cochlear structures. This study aimed to evaluate hearing preservation in children implanted with the Nucleus Slim Straight (CI422) electrode. METHODS: Nineteen children aged 6-18 years, with partial deafness, were implanted using the 6-step Skarzynski procedure. Electrode insertion depth was 20-25 mm. Hearing status was assessed with pure tone audiometry before surgery, and at 1, 5, 9, 12 and 24 months after surgery. Electrode placement was confirmed with computed tomography. RESULTS: Mean hearing preservation in the study group at activation of the cochlear implant was 73 per cent (standard deviation = 37 per cent). After 24 months, it was 67 per cent (standard deviation = 45 per cent). On a categorical scale, hearing preservation was possible in 100 per cent of cases. CONCLUSION: Hearing preservation in children implanted with the Nucleus CI422 slim, straight electrode is possible even with 25 mm insertion depth, although the recommended insertion depth is 20 mm. A round window approach using a soft, straight electrode is most conducive to hearing preservation.

Deep insertion - round window approach by using SRA electrode.

Hearing preservation surgery requires specially a traumatic technique. Having some preoperative anatomical data of the size of patient's cochlea surgeon can design his or her insertion depth. In the study we have evaluated a relation between hearing preservation rate and angular insertion depth estimated intraoperatively and postoperatively having measured insertion angle from radiological assessment and calculations given by Escude. There has not been no statistically significant difference between insertion depth angle, either estimated intraoperatively and measured and calculated post-operatively, and hearing preservation rate in the group. This analysis confirms a traumaticy of insertion in hearing preservation surgery.

Decay chains and photofission investigation based on nuclear spectroscopy of highly enriched uranium sample.

Nuclear spectroscopy experiments were performed for 100g metallic uranium rod enriched to 93% (235)U, in order to establish and characterize the most prominent γ-rays in the natural decay series and photofission reaction. Single γ-ray spectra and γ-γ coincidences measurements were conducted before irradiation. The uranium sample was subsequently irradiated with 15 MeV bremsstrahlung photons. Relative intensities of γ-lines and several values of half-lives of the fission fragments decays were determined. The obtained information can be utilized in detection of smuggled nuclear materials and characterization of bulky nuclear waste packages.

Anomalous Nernst effect in the ferromagnetic Kondo lattice Ce3RhSi3.

The ferromagnetic heavy fermion compound Ce3RhSi3 was studied by means of electrical resistivity, Hall effect, thermoelectric power and Nernst coefficient measurements. Below T ≈ 30 K, all the transport characteristics were found to behave anomalously as functions of temperature and magnetic field. In particular, the Hall and Nernst coefficients at low temperatures exhibit pronounced and strongly field-dependent maxima, likely possessing the same microscopic origin, which however cannot be captured by available theoretical models.

Nernst effect measurements of epitaxial Y0.95Ca0.05Ba2(Cu1-xZnx)3Oy and Y0.9Ca0.1Ba2Cu3Oy superconducting films.

We report Nernst effect data for crystalline films of Y0.95Ca0.05Ba2(Cu1-xZnx)3Oy (with x=0, 0.02, and 0.04) and Y0.9Ca0.1Ba2Cu3Oy grown by pulsed laser deposition. We show that our own results and published data for LSCO are consistent with the theory of Gaussian superconducting fluctuations. We also show that Zn doping increases the Nernst coefficient simply because it reduces the in-plane conductivity.

[Evaluation of ultraviolet radiation reflectance for human skin]. / Ocena wspólczynnika odbicia promieniowania ultrafioletowego dla skóry ludzkiej.

In a group of 20 males aged 19-20 years ultraviolet radiation reflectance of different wavelength (250-400 nm) from skin surface was measured. It was found that the reflectance increased monotonically with the decrease of wavelength. The reflectance values were compared with the coefficient of relative spectral biological effectiveness and significance of both values for evaluation of human exposure to ultraviolet radiation was discussed.

[Ultraviolet radiation in selected computer monitoring]. / Emisja promieniowania UV wybranych monitorów komputerowych.

Bearing in mind that computer monitors have become quite popular nowadays among both professionals and hobbyists, the authors analysed the UV radiation emitted by them. Chromatic and monochromatic monitors were used in the study. The ultraviolet radiation of monitors was compared with the UV emission of sterilamps and fluorescent lamps. The same order of radiation intensity was found in all sources under study. In addition, the effectiveness of two popular screen filters in suppressing the UV emission of computer monitors was studied. The suppression of radiation was observed together with a parallel absorption of the visible part of radiation.

[Serum marker changes during the rehabilitative treatment of stomach cancer patients]. / Izmeneniia syvorotochnykh markerov v protsesse vosstanovitel'nogo lecheniia bol'nykh rakom zheludka.

The results of rehabilitative treatment received at health resort by 200 gastric cancer patients were studied. In 85 of them, radioimmunoassay was used to measure serum CEA, ferritin and gastrin levels in the course of treatment. CEA and ferritin concentrations in remission patients (12.6 +/- 5.7 ng/ml and 94,6 +/- 15.3 ng/ml, respectively) differed from those in cases of relapse (69.2 +/- 7.1 ng/ml and 361.4 +/- 46.8 ng/ml). It is suggested that serum markers levels be used as criteria of response to treatment and prognosis.