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Vopr Pitan ; (1): 27-30, 1976.
Article in Russian | MEDLINE | ID: mdl-135412

ABSTRACT

The function of the connective tissue in the skin of albino rats with the vitamin K deficiency was studied. Changes both in the cellular elements and in the fibrous structures (deranged differentiation of cellular elements, changes in the collagenformation, accumulation of acid mucopolysaccarides, etc.) were revealed. All of the mentioned changes are eliminated not only by introduction of vicasol, but also by that of alpha-tocopherol.


Subject(s)
Connective Tissue/physiopathology , Vitamin E/therapeutic use , Vitamin K Deficiency/physiopathology , Animals , Cell Differentiation , Connective Tissue/metabolism , DNA/metabolism , Glycosaminoglycans/metabolism , Iron/metabolism , Male , Polysaccharides/metabolism , Rats , Skin/physiopathology , Vitamin K/therapeutic use , Vitamin K Deficiency/drug therapy , Vitamin K Deficiency/metabolism
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