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1.
Bull Exp Biol Med ; 148(2): 266-9, 2009 Aug.
Article in English | MEDLINE | ID: mdl-20027344

ABSTRACT

Anaferon (pediatric formulation) reduces the incidence of acute respiratory viral infections in sickly children and children with bronchial asthma and has a positive effect on the course of asthma. The preparation produces an immunomodulating effect (increases initially low IFN-gamma levels and normalizes elevated levels of IL-1beta), stimulates synthesis of IgA and IgG, exhibits cytoprotective activity, and improves local immunity of the upper airways in sickly children.


Subject(s)
Antibodies/therapeutic use , Antiviral Agents/therapeutic use , Asthma/drug therapy , Respiratory Tract Infections/blood , Respiratory Tract Infections/prevention & control , Antibodies/pharmacology , Antiviral Agents/pharmacology , Asthma/virology , Child , Child, Preschool , Female , Humans , Immune System/drug effects , Immunoglobulin A/blood , Immunoglobulin A/metabolism , Immunoglobulin G/blood , Immunoglobulin G/metabolism , Interferon-gamma/blood , Interleukin-1beta/blood , Male , Respiratory Tract Infections/drug therapy , Respiratory Tract Infections/metabolism , Treatment Outcome
2.
Article in Russian | MEDLINE | ID: mdl-17201218

ABSTRACT

We studied efficacy of using intensive physical conditioning as prophylaxis of respiratory diseases in young children and health status of children exposed to physical conditioning in childhood (a total of 44 children aged from 1.5 months to 1 year; 58 children aged from 2.5 to 13.5 years). The proposed method of conditioning significantly diminished incidence of respiratory infections, enhanced local immunity of the upper respiratory tract and prevented development of chronic diseases at later age.


Subject(s)
Adaptation, Physiological/physiology , Physical Fitness/physiology , Respiratory Tract Infections/prevention & control , Adolescent , Child , Child, Preschool , Humans , Immunoglobulin A/immunology , Leukocyte Count , Muramidase/metabolism , Nasal Mucosa/cytology , Nasal Mucosa/enzymology , Nasal Mucosa/immunology , Neutrophils/cytology , Prospective Studies , Respiratory Tract Infections/blood , Respiratory Tract Infections/immunology , Respiratory Tract Infections/metabolism , Retrospective Studies
3.
Article in Russian | MEDLINE | ID: mdl-12630360

ABSTRACT

A total of 100 children with bronchopulmonary diseases were examined. Of these, in 80 bronchial asthma and in 20 children acute pneumonia were diagnosed. The deficiency of local cell mediated and humoral factors on the mucous membranes of the upper respiratory tracts was established. In the squamous and columnar epithelium cells an increased destruction and cytolysis was noted leading to disturbances in the integrity of the protective barrier of the epithelial cover. In addition, this study revealed the deficiency of neutrophilic leukocytes, pronounced local eosinophilia and the low level of humoral protective factors. In acute pneumonia an increase in the amount of neutrophilic leukocytes in the secretion of the nasal cavity together with the appearance of destructive processes in epithelial cells took place. Pronounced deficiency in serum IgA and IgG was accompanied by compensatory increase in secretory IgA.


Subject(s)
Asthma/immunology , Pneumonia/immunology , Respiratory Mucosa/immunology , Acute Disease , Adolescent , Asthma/blood , Cell Count , Child , Eosinophils/cytology , Epithelial Cells/pathology , Female , Humans , Immunoglobulin A/blood , Immunoglobulin A, Secretory/analysis , Immunoglobulin G/blood , Male , Neutrophils/cytology , Pneumonia/blood , Respiratory Mucosa/metabolism , Respiratory Mucosa/pathology , Saliva/immunology
4.
Article in Russian | MEDLINE | ID: mdl-9643136

ABSTRACT

Inhalations of 1% natural brine in combination with SMC electrophoresis of 1% natural brine above the lesion proved to ensure good correction of the defense of respiratory tract mucosa and to prolong remission to 15-18 months. This method can be applied in sanatoria, in rehabilitation centers, in pulmonary disease departments.


Subject(s)
Electric Stimulation Therapy/methods , Pneumonia/rehabilitation , Salts/therapeutic use , Adolescent , Aerosols , Bronchitis/immunology , Bronchitis/rehabilitation , Child , Chronic Disease , Combined Modality Therapy , Humans , Immunoglobulin A, Secretory/analysis , Nasal Mucosa/immunology , Nasal Mucosa/metabolism , Pneumonia/immunology , Remission Induction , Sputum/immunology
5.
Article in Russian | MEDLINE | ID: mdl-9190746

ABSTRACT

Combined use of tubage with 2% solution of natural agent Shirsal and thermovibromassage of the right hypochondrium area for biliary dyskinesia promotes normalization of biliary system motility. The course of the procedures enhances the positive clinical trend and induces remission which persists for 6-8 months.


Subject(s)
Biliary Dyskinesia/rehabilitation , Hot Temperature/therapeutic use , Massage/methods , Vibration/therapeutic use , Adolescent , Biliary Dyskinesia/physiopathology , Child , Cholagogues and Choleretics/administration & dosage , Chronic Disease , Combined Modality Therapy , Health Resorts , Humans , Liver Circulation , Mineral Waters/administration & dosage , Salts/administration & dosage , Siberia , Solutions
6.
Article in Russian | MEDLINE | ID: mdl-9446308

ABSTRACT

Intensive conditioning significantly stimulates defensive factors of local and systemic immunity and aroused levels of stress hormones. In initial deficient resistance intensive training causes exhaustion of defensive reserves of child's body.


Subject(s)
Immunity/physiology , Physical Fitness/physiology , Adolescent , Child , Child, Preschool , Exercise/physiology , Humans , Immunoglobulins/analysis , Nasal Mucosa/immunology , Nasal Mucosa/metabolism , Time Factors
7.
Article in Russian | MEDLINE | ID: mdl-8236916

ABSTRACT

Infants with bronchial obstruction (BO) received differentiated regimens of physiotherapy. Spastic BO was managed most successfully by a complex involving ultrasonic inhalation of broncholytics and sinusoidal modulated currents. In BO with a hypersecretory component the best results were achieved with combination of UHF electromagnetic field plus ultrasonic saline-alkaline inhalations given in 2 steps.


Subject(s)
Bronchitis/rehabilitation , Bronchial Spasm/rehabilitation , Bronchiolitis/rehabilitation , Child, Preschool , Combined Modality Therapy , Drug Therapy, Combination , Humans , Infant , Physical Therapy Modalities , Remission Induction
10.
Pediatriia ; (5): 29-32, 1990.
Article in Russian | MEDLINE | ID: mdl-2399063

ABSTRACT

Children with allergic bronchitis and bronchial asthma underwent exercise therapy and training carried out on a regular basis for 9 to 15 months, which resulted in the disease relief, raised exercise tolerance, and promoted normalization of the local defence factors of the respiratory mucosa.


Subject(s)
Asthma/therapy , Bronchitis/therapy , Exercise Therapy , Nasal Mucosa/immunology , Respiration/physiology , Adolescent , Asthma/immunology , Asthma/physiopathology , Bronchitis/immunology , Bronchitis/physiopathology , Child , Child, Preschool , Humans , Immunoglobulin A, Secretory/analysis , Muramidase/analysis
11.
Lab Delo ; (3): 26-9, 1989.
Article in Russian | MEDLINE | ID: mdl-2469834

ABSTRACT

Confidence intervals have been used to derive the reference values of certain immune status parameters in children. Mathematical analysis has helped define such values for every age group. These values permit singling out children with normal or mean values of these parameters and with deviations from the norm in respect of the immunity status.


Subject(s)
Ambulatory Care , Immunity , Population Surveillance , Adolescent , Child , Child, Preschool , Humans , Infant , Reference Values , USSR
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