ABSTRACT
A complex simultaneous assessment of the microbiota (the aerobic and anaerobic links as well as the parietal and lumen components) of the gutter, vagina, and intestines of women with a pathological pregnancy was performed. In 30% of women the study revealed system dysbiotic changes. Local immune reactivity was decreased, which may be considered a provoking factor. In conclusion, complex microbiological examination makes it possible to objectivize the picture of the pathological process and its outcome. A criterion for the administration of correcting measures is offered.
Subject(s)
Abortion, Threatened/microbiology , Abortion, Threatened/pathology , Bacteria/isolation & purification , Intestines/microbiology , Oropharynx/microbiology , Pregnancy Trimester, First , Vagina/microbiology , Biopsy , Colony Count, Microbial , Female , Humans , Intestines/pathology , Oropharynx/pathology , Pregnancy , Risk Factors , Vagina/pathologyABSTRACT
Thirteen patients with generalized purulent peritonitis were treated with multiple staging sanation of abdominal cavity and special bacteriophages with high activity to 4 nosocomial bacterium strains. The phages permitted to prevent infection with these nosocomial strains. Three new phages with high bacteriolytic activity were identified. Antibacterial activity "in vitro" of all phages was higher than antibiotic susceptibility. It is concluded that bacteriophages are promising method of treatment and prevention of complications associated with nosocomial infection at surgical patients with long-time purulent processes.
