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1.
Sci Adv ; 9(32): eadg4609, 2023 Aug 11.
Article in English | MEDLINE | ID: mdl-37566658

ABSTRACT

Spin waves are ideal candidates for wave-based computing, but the construction of magnetic circuits is blocked by a lack of an efficient mechanism to excite long-running exchange spin waves with normalized amplitudes. Here, we solve the challenge by exploiting a deeply nonlinear phenomenon for forward volume spin waves in 200-nm-wide nanoscale waveguides and validate our concept using microfocused Brillouin light scattering spectroscopy. An unprecedented nonlinear frequency shift of more than 2 GHz is achieved, corresponding to a magnetization precession angle of 55° and enabling the excitation of spin waves with wavelengths down to 200 nm. The amplitude of the excited spin waves is constant and independent of the input microwave power due to the self-locking nonlinear shift, enabling robust adjustment of the spin-wave amplitudes in future on-chip magnonic integrated circuits.

2.
Phys Rev E ; 105(5-1): 054601, 2022 May.
Article in English | MEDLINE | ID: mdl-35706172

ABSTRACT

Supramolecular magnetic polymerlike (SMP) structures are nanoscaled objects that combine the flexibility of polymeric conformations and controllability of magnetic nanoparticles. The advantage provided by the presence of permanent cross-linkers is that even at high temperature, a condition at which entropy dominates over magnetic interactions, the length and the topology of the SMP structures are preserved. On cooling, however, preexistent bonds constrain thermodynamically equilibrium configurations, making a low-temperature regime for SMP structures worth investigating in detail. Moreover, making SMP structures with perfectly monodisperse monomers has been a challenge. Thus, the second open problem in the application of SMP structures is the missing understanding of the polydispersity impact on their structural and magnetic properties. Here extensive Langevin dynamics simulations combined with parallel tempering method are used to investigate SMP structures of four different types, i.e., chainlike, Y-like, X-like, and ringlike, composed of monomers of two different sizes. Our results show that the presence of small particles in SMP structures can qualitatively change the magnetic response at low temperature, making those structures surprisingly more magnetically responsive than their monodisperse counterparts.

3.
J Clin Oncol ; 38(30): 3547-3554, 2020 10 20.
Article in English | MEDLINE | ID: mdl-32795227

ABSTRACT

PURPOSE: To analyze the prevalence of SARS-CoV-2 infection in patients with cancer in hospital care after implementation of institutional and governmental safety measurements. METHODS: Patients with cancer routinely tested for SARS-CoV-2 RNA by nasal swab and real-time polymerase chain reaction between March 21 and May 4, 2020, were included. The results of this cancer cohort were statistically compared with the SARS-CoV-2 prevalence in the Austrian population as determined by a representative nationwide random sample study (control cohort 1) and a cohort of patients without cancer presenting to our hospital (control cohort 2). RESULTS: A total of 1,688 SARS-CoV-2 tests in 1,016 consecutive patients with cancer were performed. A total of 270 of 1,016 (26.6%) of the patients were undergoing active anticancer treatment in a neoadjuvant/adjuvant and 560 of 1,016 (55.1%) in a palliative setting. A total of 53 of 1,016 (5.2%) patients self-reported symptoms potentially associated with COVID-19. In 4 of 1,016 (0.4%) patients, SARS-CoV-2 was detected. At the time of testing at our department, all four SARS-CoV-2-positive patients were asymptomatic, and two of them had recovered from symptomatic COVID-19. Viral clearance was achieved in three of the four patients 14-56 days after testing positive. The estimated odds ratio of SARS-CoV-2 prevalence between the cancer cohort and control cohort 1 was 1.013 (95% CI, 0.209 to 4.272; P = 1), and between control cohort 2 and the cancer cohort it was 18.333 (95% CI, 6.056 to 74.157). CONCLUSION: Our data indicate that continuation of active anticancer therapy and follow-up visits in a large tertiary care hospital are feasible and safe after implementation of strict population-wide and institutional safety measures during the current COVID-19 pandemic. Routine SARS-CoV-2 testing of patients with cancer seems advisable to detect asymptomatic virus carriers and avoid uncontrolled viral spread.


Subject(s)
Betacoronavirus/isolation & purification , Coronavirus Infections/diagnosis , Neoplasms/virology , Pneumonia, Viral/diagnosis , Adolescent , Adult , Aged , Aged, 80 and over , COVID-19 , Cohort Studies , Female , Humans , Male , Middle Aged , Neoplasms/drug therapy , Pandemics , SARS-CoV-2 , Tertiary Care Centers , Young Adult
4.
Phys Rev Lett ; 95(12): 123003, 2005 Sep 16.
Article in English | MEDLINE | ID: mdl-16197072

ABSTRACT

We propose to quantify the correlation inherent in a many-electron (or many-fermion) wave function psi by comparing it to the unique uncorrelated state that has the same 1-particle density operator as does /|psi>

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