ABSTRACT
OBJECTIVE: Uric acid to albumin ratio (UAR) reflects inflammatory activity and its predictive value has been shown in various diseases. In this study, we sought to evaluate the value of uric acid to albumin ratio in patients with peripheral arterial disease (PAD). PATIENTS AND METHODS: Two hundred forty-three PAD patients were divided into TransAtlantic Inter-Society Consensus-II (TASC-II) A-B and TASC-II C-D groups, according to their TASC-II classification. Biochemical variables of the patients were recorded, and the UAR of each patient was calculated. RESULTS: Patients who had TASC-II A-B disease were younger than the patients who had TASC-II C-D disease (60.7±8.71 vs. 63.28±8.8 years, p=0.024). Quade ANCOVA results showed that patients with TASC-II C-D disease had higher values of UAR when age was used as a covariate (t=-5.045, p<0.001). Lymphocyte count was significantly lower, and UAR was significantly higher in patients with TASC-II C-D disease (p=0.035 and p<0.001, respectively). UAR and lymphocyte count showed a significant positive correlation and a negative correlation with the TASC-II class of the disease (r=0.403, and r=-0.299, p<0.001 for both). A UAR of 1.54 predicted TASC-II C-D disease with a sensitivity and specificity of 57.9% and 78.8%, respectively. UAR predicted severe PAD with an OR of 3.723. CONCLUSIONS: UAR was a better tool for predicting TASC-II C-D disease compared to uric acid and albumin levels. UAR is an easily calculable parameter that can be used in clinical practice.
Subject(s)
Peripheral Arterial Disease , Uric Acid , Humans , Treatment Outcome , Peripheral Arterial Disease/diagnosis , Albumins , Registries , Femoral Artery , Retrospective Studies , Vascular Patency , StentsABSTRACT
Algae and cyanobacteria are capable living under harsh conditions in the natural environments and can develop peculiar survival processes. In order to evaluate radiation shielding properties of green algae; Chlorella vulgaris, Scenedesmus obliquus, and cyanobacteria; Synechococcus sp., Planktothrix limnetica, Microcystis aeruginosa, Arthrospira maxima, Anabaena affinis, Phormidium articulatum, and Pseudoanabaena sp. were cultured in batch systems. Air dried biomass was tested for its high tolerance to gamma-radiations in terms of linear attenuation coefficients. In the present work, the linear and mass attenuation coefficients were measured at photon energies of 1173 and 1332 keV. Protection capacity of some biomass was observed to be higher than a 1-cm thick lead standard for comparison. Gamma ray related protection depends not only to thickness but also to density (g/cm3). Hence the effect of biomass density also was tested and significantly found the tested biomass absorbed more of the incoming energy on a density basis than lead. This paper discusses the a new approach to environmental protection from gamma ray. The findings suggest that the test samples, especially cyanobacteria, have a potential for reducing gamma ray more significantly than lead and can be used as shielding materials.