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1.
Lik Sprava ; (5-6): 55-7, 2001.
Article in Russian | MEDLINE | ID: mdl-11881381

ABSTRACT

Studied among indices for the glutathione system in 99 patients was content of total, oxidized, reduced glutathione. The studies made suggested that in patients beyond 60 years of age there are profound inadequecies in the glutathione system manifested by an apparent reduction in total, reduced glutathione and augmentation of the oxidized form in the blood. Surgical treatment in the above patient population has not been found to be associated with bringing all studied forms of glutathione back to normal, which fact attests to the need for quest of drugs-antioxidants to be employed in the complex of postsurgery curative measures.


Subject(s)
Glutathione/metabolism , Peptic Ulcer/physiopathology , Peptic Ulcer/surgery , Pyloric Stenosis/physiopathology , Pyloric Stenosis/surgery , Adolescent , Adult , Aged , Cohort Studies , Female , Glutathione/blood , Humans , Male , Middle Aged , Oxidation-Reduction , Peptic Ulcer/pathology , Pyloric Stenosis/pathology
2.
Khirurgiia (Mosk) ; (7): 34-6, 2000.
Article in Russian | MEDLINE | ID: mdl-10958066

ABSTRACT

Investigation of autonomic nervous system tonicity has been undertaken in 34 healthy persons (control group I), in 30 patients with non-complicated duodenal ulcer (control group 2), 38 patients with complicated gastroduodenal ulcer (10--with perforation, 13--with bleeding, 15--with stenosis) and 32 patients in the long-term period. The patients age was from 17 to 75 years. 72 patients were males and 28--females. Results of the study showed, that among the patients with complicated gastroduodenal ulcer there were eutonics and sympathicotonics, among those with non-complicated ulcer disease sympathotonics prevailed. To predict occurrence of complicated ulcer, determination of the tone of vegetative nervous system in patients with non-complicated ulcer in period between attacks is recommended. Identification of phenotype characteristics of vegetative nervous system tone allows to predict development of possible postoperative complications in patients with gastroduodenal ulcer.


Subject(s)
Duodenal Obstruction/physiopathology , Duodenal Ulcer/physiopathology , Peptic Ulcer Hemorrhage/physiopathology , Sympathetic Nervous System/physiopathology , Adolescent , Adult , Aged , Duodenal Obstruction/etiology , Duodenal Ulcer/complications , Female , Humans , Male , Middle Aged , Prognosis
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