Threefold Increase of the Bulk Electron Temperature of Plasma Discharges in a Magnetic Mirror Device.

This Letter describes plasma discharges with a high temperature of bulk electrons in the axially symmetric high-mirror-ratio (R=35) open magnetic system gas dynamic trap (GDT) in the Budker Institute (Novosibirsk). According to Thomson scattering measurements, the on-axis electron temperature averaged over a number of sequential shots is 660±50 eV with the plasma density being 0.7×10^{19} m^{-3}; in few shots, electron temperature exceeds 900 eV. This corresponds to at least a threefold increase with respect to previous experiments both at GDT and at other comparable machines, thus, demonstrating the highest quasistationary (about 1 ms) electron temperature achieved in open traps. The breakthrough is made possible by application of a new 0.7 MW/54.5 GHz electron cyclotron resonance heating system in addition to standard 5 MW heating by neutral beams, and application of a radial electric field to mitigate the flute instability.

Progress in Mirror-Based Fusion Neutron Source Development.

The Budker Institute of Nuclear Physics in worldwide collaboration has developed a project of a 14 MeV neutron source for fusion material studies and other applications. The projected neutron source of the plasma type is based on the gas dynamic trap (GDT), which is a special magnetic mirror system for plasma confinement. Essential progress in plasma parameters has been achieved in recent experiments at the GDT facility in the Budker Institute, which is a hydrogen (deuterium) prototype of the source. Stable confinement of hot-ion plasmas with the relative pressure exceeding 0.5 was demonstrated. The electron temperature was increased up to 0.9 keV in the regime with additional electron cyclotron resonance heating (ECRH) of a moderate power. These parameters are the record for axisymmetric open mirror traps. These achievements elevate the projects of a GDT-based neutron source on a higher level of competitive ability and make it possible to construct a source with parameters suitable for materials testing today. The paper presents the progress in experimental studies and numerical simulations of the mirror-based fusion neutron source and its possible applications including a fusion material test facility and a fusion-fission hybrid system.

Spatial pattern formation in external noise: theory and simulation.

Spatial pattern formation in fluctuating media is researched analytically from the point of view of the order parameters concept. A reaction-diffusion system with external noise is considered as a model of such media. Stochastic equations for unstable mode amplitudes (order parameters), the dispersion equation for averaged amplitudes of unstable modes, and the Fokker-Planck equation for the order parameters are obtained. The theory developed makes it possible to analyze different noise-induced effects including the variation of boundaries of ordering and disordering phase transitions depending on the parameters of external noise.

Experimental evidence of high-beta plasma confinement in an axially symmetric gas dynamic trap.

In the axially symmetric magnetic mirror device gas dynamic trap (GDT), on-axis transverse beta (ratio of the transverse plasma pressure to magnetic field pressure) exceeding 0.4 in the fast ion turning points has been first achieved. The plasma has been heated by injection of neutral beams, which at the same time produced anisotropic fast ions. Neither enhanced losses of the plasma nor anomalies in the fast ion scattering and slowing down were observed. This observation confirms predicted magnetohydrodynamic stability of plasma in the axially symmetric mirror devices with average min-B, like the GDT is. The measured beta value is rather close to that expected in different versions of the GDT based 14 MeV neutron source for fusion materials testing.

Differences in amplitude-voltage relations between minimal and composite mossy fibre responses of rat CA3 hippocampal neurons support the existence of intrasynaptic ephaptic feedback in large synapses.

Computer simulations and electrophysiological experiments have been performed to test the hypothesis on the existence of an ephaptic interaction in purely chemical synapses. According to this hypothesis, the excitatory postsynaptic current would depolarize the presynaptic release site and further increase transmitter release, thus creating an intrasynaptic positive feedback. For synapses with the ephaptic feedback, computer simulations predicted non-linear amplitude-voltage relations and voltage dependence of paired-pulse facilitation. The deviation from linearity depended on the strength of the feedback determined by the value of the synaptic cleft resistance. The simulations showed that, in the presence of the intrasynaptic feedback, recruitment of imperfectly clamped synapses and synapses with linear amplitude-voltage relations tended to reduce the non-linearity and voltage dependence of paired-pulse facilitation. Therefore, the simulations predicted that the intrasynaptic feedback would particularly affect small excitatory postsynaptic currents induced by activation of electrotonically close synapses with long synaptic clefts. In electrophysiological experiments performed on hippocampal slices, the whole-cell configuration of the patch-clamp technique was used to record excitatory postsynaptic currents evoked in CA3 pyramidal cells by activation of large mossy fibre synapses. In accordance with the simulation results, minimal excitatory postsynaptic currents exhibited "supralinear" amplitude-voltage relations at hyperpolarized membrane potentials, decreases in the failure rate and voltage-dependent paired-pulse facilitation. Composite excitatory postsynaptic currents evoked by activation of a large amount of presynaptic fibres typically bear linear amplitude-voltage relationships and voltage-independent paired-pulse facilitation. These data are consistent with the hypothesis on a strong ephaptic feedback in large mossy fibre synapses. The feedback would provide a mechanism whereby signals from large synapses would be amplified. The ephaptic feedback would be more effective on synapses activated in isolation or together with electrotonically remote inputs. During synchronous activation of a large number of neighbouring inputs, suppression of the positive intrasynaptic feedback would prevent abnormal boosting of potent signals.

Environmental factors which may have led to the appearance of colour vision.

It is hypothesized that colour vision and opponent processing of colour signals in the visual system evolved as a means of overcoming the extremely unfavourable lighting conditions in the natural environment of early vertebrates. The significant flicker of illumination inherent in the shallow-water environment complicated the visual process in the achromatic case, in particular preventing early detection of enemies. The presence of two spectral classes of photoreceptors and opponent interaction of their signals at a subsequent retinal level allowed elimination of the flicker from the retinal image. This new visual function provided certain advantages concerning reaction times and favoured survival. This assumption explains why the building blocks for colour vision arose so early, i.e. just after the active predatory lifestyle was mastered. The principal functions of colour vision inherent in extant animals required a more complex neural machinery for colour processing and evolved later as the result of a change in visual function favouring colour vision.

Horizontal cell dynamics: what are the main factors?

The factors potentially determining the dynamics of horizontal cell (HC) responses are: (1) the rate of transmitter release (including its transient component) and removal; (2) the voltage non-linearity of HC non-synaptic membrane combined with its capacitance; and (3) the dynamics of feedback from HCs to photoreceptors. Using, in consecutive order, the models of an isolated HC, a HC with one or two synaptic inputs and a HC of chromatic type, we have analysed the relative importance of three factors in shaping HC responses to the light and electrical current. The most prominent effect on the shape of HC ON responses derives from the voltage-dependency of the non-synaptic membrane. The dynamics of synaptic transmission plays a leading role in shaping the OFF light responses. For depolarizing responses of C-type HCs, the key factor is the electrical feedback from L-type HCs, which provides not only the response of opposite polarity (to red light), but also the typical feedback delay.

Small passerines can discriminate ultraviolet surface colours.

Hollow-dwelling passerine birds were tested for UV surface colour discrimination by using the instinct to bring food to nestlings that makes a bird search for the nest under changing conditions. The experiments were carried out on breeding pairs of pied flycatcher (Muscicapa hypoleuca), great tit (Parus major) and tree sparrow (Passer montanus) in the wild by the method of alternative choice of entrance into a double nesting-box with the nestlings in one or the other section. The entrances were marked with sheets of painted papers that had different reflectances in UV. For a human observer, all marks looked achromatic. Birds were trained to discriminate the mark coloured with UV-absorbing paint from a neutral one (with equal reflectance throughout the spectrum). Birds easily learned to search for the UV-absorbing mark, and transferred the acquired habit when tested with new marks that differed only slightly from the initial ones in lightness to eliminate brightness cues.

Chromatic properties of the retinal afferents in the thalamus and the tectum of the frog (Rana temporaria).

In order to clarify physiological mechanisms underlying colour-specific visually guided behaviour, we measured spectral sensitivities of On-fibres projecting to the thalamus and class 2 and 3 fibres passing to tectum opticum. In addition we recorded responses of these fibres to moving coloured papers with known spectral reflectancies. The latter method, here called paper colourimetry, allowed us to change the relative stimulations of the blue-, green- and red-sensitive photoreceptors in any direction desired. Under the photopic conditions used the tectal fibres were driven exclusively by red-sensitive receptors, while the thalamic fibres received strong On-inputs from both red- and blue-sensitive receptors. Due to a partly antagonistic interaction between these inputs the On-fibres acted in a dichromatic way, responding with specific extended low-frequency discharges to all relative increases in blue receptor stimulation, e.g. to a great reduction in red stimulation combined with unchanged blue stimulation. Thus they have functional characteristics which could serve a visual system showing colour constancy.