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1.
Stud Health Technol Inform ; 159: 234-8, 2010.
Article in English | MEDLINE | ID: mdl-20543442

ABSTRACT

This work determines the molecular epidemiology of dengue virus in Venezuela by means of phylogenetic calculations performed on the EELA-2 Grid infrastructure with the PhyloGrid application, an open source tool that allows users performing phylogeny reconstruction in their research. In this study, a total of 132 E nucleotide gene sequences of dengue virus from Venezuela recorded in GenBank(R) have been processed in order to reproduce and validate the topology described in the literature.


Subject(s)
Antigenic Variation , Computer Communication Networks , Dengue Virus/genetics , Bayes Theorem , Phylogeny , User-Computer Interface , Venezuela
2.
Stud Health Technol Inform ; 147: 245-50, 2009.
Article in English | MEDLINE | ID: mdl-19593062

ABSTRACT

In this work we demonstrate the adequacy of revising the classification systems based on molecular phylogenetic calculations by allowing an arbitrary number of taxas that take advantage of high performance computing platforms for the Human papillomavirus (HPV) case. To do so, we have analysed several phylogenetic trees which have been calculated with the PhyloGrid tool, a workflow developed in the framework of the EELA-2 Project.


Subject(s)
Papillomaviridae/genetics , Phylogeny , Humans , Papillomaviridae/classification
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