ABSTRACT
We studied structural changes in the prostate gland, thymus, and lymph nodes in CBA mice after transplantation of Ehrlich ascites tumor cells into the prostate gland. On experimental day 5, the number of blood and lymph vessels decreased in the gland; the percentage of connective tissue elements and glandular tissue and the number of immunoblasts in the thymus increased. On day 18, the number of blood vessels in the tumor decreased; the width of the cortex and glandular tissue increased in the thymus, while the number of immunoblasts was reduced. On day 28, tumor infiltration and increased number of lymphatic vessels in its stroma were observed; parenchyma was reduced, and the area of the connective tissue increased in the thymus. These structural changes indicated the development of accidental involution of the thymus during carcinogenesis of the prostate.
Subject(s)
Carcinogenesis/pathology , Carcinoma, Ehrlich Tumor/physiopathology , Lymph Nodes/physiopathology , Prostate/physiopathology , Prostatic Neoplasms/physiopathology , Thymus Gland/anatomy & histology , Thymus Gland/physiopathology , Animals , Carcinogenesis/metabolism , Carcinoma, Ehrlich Tumor/blood supply , Connective Tissue/growth & development , Male , Mice , Mice, Inbred CBA , Prostate/metabolism , Prostatic Neoplasms/blood supplyABSTRACT
An entrance surface of a multimode optical fiber with the highest efficiency of coupling radiation from a laser diode is considered. The geometry of the surface is designed with the purpose of keeping a refracted ray inside the fiber with simultaneous minimization of the reflection coefficient in each point of the surface. As a good approximation to the ideal surface, the composite entrance surface of a cylinder-wedge shape is proposed. It has clearly improved the coupling efficiency as compared with that of the purely cylindrical surface. Analysis of the entrance surfaces is based on their transmission coefficients, depending on the incident ray direction.
