1.
Eur J Immunol
; 51(7): 1857-1859, 2021 07.
Article
in English
| MEDLINE
| ID: mdl-33772780
ABSTRACT
T-cell accumulation in atherosclerotic plaques contributes to plaque destabilization. We found that several chemokine receptors are differentially expressed on peripheral blood compared to plaque-resident T cells and corresponding ligands are upregulated in plaques. These data indicate that T-cell migration into human atherosclerotic plaques may predominantly occur via CCR5-CCL3 and CX3CR1-CX3CL1 interactions.