An efficient catalysis for the synthesis of pyrimido[1,2-a]benzimidazoles and 1-(benzothiazolylamino)methyl-2-naphthols using ZnO@SO3H@Tropine.

In this research and in the line of our researches on the use of nano-substrates modified with ionic liquid in organic reactions, an efficient and green method for the one-pot three-component synthesis of pyrimido[1,2-a]benzimidazole and 1-(benzothiazolylamino)methyl-2-naphthol derivatives is reported using a new nanoporous catalyst formulated as ZnO@SO3H@Tropine. Further analysis of the catalyst for its characterization has been performed using thermal gravimetric analysis (TGA), field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), energy dispersive spectrometer (EDS) and Fourier-transform infrared spectroscopy (FT-IR). The present approach creates a variety of biologically active heterocyclic compounds with excellent yields and short reaction times. Among the other advantages of the current method are: ease of operation, clean reaction profiles and ease of separation. Also, this catalyst can be reused five times without loss of its catalytic activity.

Copper salt of a DABCO-based molten salt: a high-performance catalyst in the one-pot synthesis of 3,4-dihydropyrimidine and polyhydroquinoline derivatives.

In this study, [DABCO](SO3H)2CuCl4 as a novel DABCO-based molten salt with dual acidic functionality (Brønsted and Lewis) has been synthesized, characterized and used as a high-performance catalyst in the one-pot synthesis of 3,4-dihydropyrimidine and polyhydroquinoline derivatives. The identification of this catalyst was accomplished by using techniques such as infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermo gravimetric analysis (TGA), field emission scanning electron microscopy (FESEM) and energy dispersive X-ray (EDS) spectroscopy. Excellent efficiency, short reaction times, a simple working method and also use of a recyclable catalyst are the considerable advantages of this process.

Facile and Efficient Synthesis of Tetrahydrobenzimidazo [2,1-b]Quinazolin-1(2H)-One Derivatives Using Brönsted Acidic Ionic Liquid Immobilized on Nanoporous Na+-Montmorillonite.

In this work, an efficient and green procedure have been described for the synthesis of tetrahydrobenzimidazo[2,1-b]quinazolin-1(2H)-one derivatives using nanoporous sodium montmorillonite clay (Na+-MMT) modified with 1-methyl-3-(trimethoxysilylpropyl)-imidazolium hydrogen sulfate (Na+-MMT-[pmim]HSO4). The procedure gave the products in excellent yields in very short reaction times under solvent-free condition. Also this catalyst can be reused for six times without considerable loss of its catalytic activity.