ABSTRACT
BACKGROUND: An increasing number of papers have documented the contribution of chronic periodontitis (P) to the pathogenesis of cardiovascular disease. The aim of this study was to answer the question whether there is an association between periodontal inflammation and atherosclerotic processes in hemodialysis patients with chronic kidney disease (CKD). METHODS: Forty-four hemodialysis patients with CKD were considered. Advanced chronic periodontitis was found in 17, whereas 27 patients had no or moderate chronic periodontitis. In all patients examined, serum C-reactive protein (CRP), TNF-alfa and IL-6 concentrations, as well as intima-media thickness (IMT) of the carotid artery, were assessed. RESULTS: Patients with CKD and advanced periodontitis were characterized by a significantly higher serum CRP concentration (13.2 +/- 11.4 vs. 10.4 +/- 14.4; p<0.05) and IMT (0.742 +/- 0.028 vs. 0.656 +/- 0.019, p<0.05) than CKD patients without periodontitis. In the univariate analysis, a significant correlation between CRP and number of atherosclerotic plaques was revealed; however, it was not confirmed as an independent relationship in the multiple regression analysis. CONCLUSIONS: Inflammation of the periodontal tissue in patients with CKD is associated with increased serum CRP concentration and greater IMT. It is possible that periodontitis may induce a systemic process that may exacerbate atherosclerosis.
Subject(s)
C-Reactive Protein/metabolism , Carotid Arteries/diagnostic imaging , Kidney Diseases/complications , Periodontitis/blood , Periodontitis/diagnostic imaging , Renal Dialysis , Adult , Chronic Disease , Female , Humans , Kidney Diseases/blood , Kidney Diseases/diagnostic imaging , Male , Middle Aged , Periodontitis/complications , Tunica Intima/diagnostic imaging , Tunica Media/diagnostic imaging , UltrasonographyABSTRACT
The general enthusiasm connected with sports activities causes that we often forget about threat connected with careless sports activities. The aim of this paper was the evaluation of causes and frequencies of maxillofacial injuries in hospitalized athletes in the Department of Maxillofacial Surgery in Katowice. Period between 1992-2002 was analyzed. Material consisted of 59 patients in whom injury required hospitalization. In studied material the frequency and causes of maxillofacial injuries in athletes in eleven-year period was examined. Male and female patients were divided in two groups: I--team sports and II--individual sports. In analyzed material injuries of upper part of facial skull were not affirmed. Injuries of upper facial massif overweighed its bottom massif injuries.