ABSTRACT
In recent years, lipofilling became a popular scar treatment method. Its beneficial outcomes have been partly attributed to the regenerative capacity of adipose-derived stem cells (ADSCs), suspended in an extracellular matrix-the stromal vascular fraction (SVF). The aim of this review was to verify if existing data support the clinical use of ADSC-related interventions in scar treatment. A systematic search of the literature was performed in July 2020 in five databases (Medline, Cochrane, Web of Science, Scopus and Embase). Articles written in English, except for reviews, letters and editorials, were identified and screened for eligibility. We looked for reports of any outcomes in scars treated with ADSCs or SVF. Data from selected articles were extracted and the quality of each study was assessed. Five hundred and fourteen studies were identified in the primary search, of which nineteen were eventually included in the systematic review. Extracted data pointed to beneficial microscopic, functional and aesthetic outcomes in a total of 665 patients. Six studies included comparative interventions-platelet-rich plasma or CO2 fractional laser. Collected data give low-to-average quality evidence for beneficial effects of ADSC-related interventions in scar treatment. Some studies suggest that these interventions are noninferior to PRP or fractional CO2 laser.
ABSTRACT
AIM: The aim of our study was to evaluate temperature differences of burns looking at their prognostic ability to predict healing at the 21 day mark. MATERIALS AND METHOD: Thirty two burns in 26 patients aged 1-71 years old were photographed with a FLIR T650 camera. Environment, reflected, and body core temperature of the patients were measured. Skin emissivity was constant 0.98. Pictures were analyzed with R&D FLIR Software. Minimal and average burn temperatures and skin temperature in 255 pixel squares were measured. Patients were divided into healed and not healed groups. Statistical analysis was performed with SPSS 20 (IBM Armonk, USA) and p<0.05 was significant. RESULTS: There were 25 healed and 7 non-healed burns at 21 days. Healed burns were significantly warmer than non-healed burns (p<0.05). There was a statistically significant strong, negative correlation between the difference of minimal burns temperatures and healthy skin temperatures with days needed to heal the burns (p=0.001; rho=-0.564). CONCLUSION: Infrared camera seems to be useful equipment in predicting burns' healing time. However further clinical studies need to be done.
Subject(s)
Burns/diagnostic imaging , Infrared Rays , Photography , Skin Temperature , Thermography , Wound Healing , Adolescent , Adult , Aged , Body Temperature , Burn Units , Child , Child, Preschool , Female , Humans , Infant , Male , Middle Aged , Pilot Projects , Prognosis , Prospective Studies , Young AdultABSTRACT
BACKGROUND: The purpose of this study was to determine the timing and type of surgical field contamination in 50 consecutive resections for advanced head and neck cancer with same-stage tissue reconstruction and to analyze the relationship between contamination and the surgical site infection. METHODS: Swabs from the surgical field and from surgical drapes close to the field were taken every 2 hours (at 0 hour, 2 hours, 4 hours, and 6 hours) and sent for a standard microbiological diagnostic procedure. Results were recorded in Microsoft Excel and analyzed with SPSS. RESULTS: We collected 336 swabs of which 71% were contaminated. Polymicrobial contamination was observed in 153 samples (45%). Twenty-six species of pathogens were found, the most frequent was Streptococcus species. Surgical site infection with positive culture occurred in 3 patients. CONCLUSION: In head and neck surgery for advanced cancer, standard aseptic procedures do not prevent contamination of the surgical field with physiological bacterial flora of the skin and oral cavity. Although contamination was common, surgical site infection was rare.
