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J Small Anim Pract ; 53(12): 709-13, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23020172

ABSTRACT

An 18-month-old male basset hound was presented with vomiting, diarrhoea and depression. Abdominal ultrasonography revealed a mass in the left kidney. An ultrasound-guided core-biopsy indicated aggregates of spindle cells, but did not allow a definitive diagnosis. Nephrectomy was performed after a period of six months, when ultrasound examination revealed a slight increase in mass dimensions. Histologically the mass was composed of neoplastic spindle cells forming interlacing fascicles, bundles and whorls, within a loose myxoid to dense collagenous stroma. Immunohistochemically neoplastic cells were positive for vimentin and smooth muscle actin. Based on these findings the tumour was diagnosed as a congenital mesoblastic nephroma, classical variant. After a two-and-a-half-year follow-up the dog was clinically healthy, indicating a benign behaviour. To the authors' knowledge, this report describes the first case of canine congenital mesoblastic nephroma successfully treated surgically, with a reasonable postsurgical follow-up.


Subject(s)
Dog Diseases/congenital , Kidney Neoplasms/veterinary , Nephroma, Mesoblastic/veterinary , Animals , Dog Diseases/diagnosis , Dog Diseases/surgery , Dogs , Immunohistochemistry/veterinary , Kidney Neoplasms/congenital , Kidney Neoplasms/diagnosis , Kidney Neoplasms/surgery , Male , Nephroma, Mesoblastic/diagnosis , Nephroma, Mesoblastic/surgery
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