ABSTRACT
AIM: 18F-Fluorodeoxyglucose positron-emission tomography integrated with computed tomography (18FDG PET-CT) is a non-invasive examination that could be helpful for the management of endometrial cancer. This study investigated the performance of 18FDG PET-CT in assessing para-aortic (PA) lymph-node involvement in high-risk endometrial cancer. MATERIALS AND METHODS: This was a retrospective, single-center study carried out between 2009 and 2018. The inclusion criteria were high-risk and locally advanced type 1 or 2 endometrial cancer with 18FDG PET-CT before PA lymphadenectomy. RESULTS: During the study period, among 142 patients with high-risk endometrial cancer, 35 patients (24.6%) underwent 18FDG PET-CT followed by PA lymphadenectomy. In 25% of cases, PA lymphadenectomy was not performed due to the discovery of metastasis. 18FDG PET-CT had a sensitivity of 50%, a specificity of 100%, a positive predictive value of 100%, a negative predictive value of 75%, accuracy of 80% and an area under the curve of 0.75 for the evaluation of PA involvement. CONCLUSION: According to its high specificity in PA lymph-node evaluation, a positive PET scan might allow PA lymphadenectomy to be avoided.
Subject(s)
Aorta/pathology , Endometrial Neoplasms/diagnostic imaging , Endometrial Neoplasms/pathology , Lymphatic Metastasis , Adult , Aged , Area Under Curve , Female , Fluorodeoxyglucose F18 , Humans , Lymph Node Excision , Lymph Nodes/pathology , Magnetic Resonance Imaging , Middle Aged , Positron Emission Tomography Computed Tomography , Predictive Value of Tests , Radiopharmaceuticals , Retrospective Studies , Sensitivity and SpecificityABSTRACT
INTRODUCTION: In children, and specifically in infants, odontogenic myxomas are extremely rare. In infants, myxoma seems to display mostly the same clinical, radiological and pathological characteristics. This paper presents a series of odontogenic myxomas in infant patients. MATERIALS AND METHODS: Four infant patients were included in this retrospective study. The clinical, radiological and pathological presentation was characterized and the treatment analysed. RESULTS: All patients presented with a rapidly evolving paranasal swelling. CT-scan showed a maxillary homogeneous unilocular and intraosseous tumour. In all cases, pathological examination revealed a loose myxoid stroma within stellate and spindle shaped cells. All patients underwent conservative surgery through a vestibular approach. CONCLUSION: This patient series and a review of the literature demonstrates that odontogenic myxoma is specific in infant. We propose the name of Infant Odontogenic Myxoma for this entity.
