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Org Biomol Chem
; 8(12): 2814-22, 2010 Jun 21.
Article
in English
| MEDLINE
| ID: mdl-20428587
ABSTRACT
A library of 4,5-disubstituted-2-aminoimidazoles was synthesized using a nitroenolate route and then screened for antibiofilm and antimicrobial activity. These compounds displayed notable biofilm dispersal and planktonic microbicidal activity against various Gram-positive and Gram-negative bacteria.