ABSTRACT
Erythrodermic cutaneous t-cell lymphoma (CTCL) is an aggressive variant of CTCL with multiple skin manifestations and symptoms. A brief overview of CTCL and a case study of one patient with erythrodermic CTCL who underwent successful treatment in a research protocol with extracorporeal photopheresis and UVADEX are presented. Nursing care, critical for patients with erythrodermic CTCL, is also described.
Subject(s)
Lymphoma, T-Cell, Cutaneous/nursing , Lymphoma, T-Cell, Cutaneous/therapy , Photopheresis/methods , Photopheresis/nursing , Aged , Humans , Male , Nursing DiagnosisABSTRACT
The Joint Commission on Accreditation of Healthcare Organizations recently approved new standards for pain assessment and management. These standards will influence the practice of dermatology nursing in every setting. Nurses play a critical role in the care of patients with pain. Pyoderma gangrenosum is used as the basis for applying the new pain standards.
Subject(s)
Pain/nursing , Pyoderma Gangrenosum/nursing , Acetaminophen/therapeutic use , Adult , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Female , Humans , Joint Commission on Accreditation of Healthcare Organizations , Leg , Narcotics/therapeutic use , Pain/drug therapy , Pain/etiology , Pain Measurement , Practice Guidelines as Topic , Pyoderma Gangrenosum/complications , United StatesSubject(s)
Biological Warfare , Health Policy , Violence , Government , Humans , United States , Violence/legislation & jurisprudenceABSTRACT
The poster exhibit is an efficient and effective educational tool. It is also an excellent means to creatively communicate new ideas, projects, and research in dermatology nursing. The advantages of the poster exhibit and guidelines for creating a poster presentation are discussed.
Subject(s)
Audiovisual Aids , Diffusion of Innovation , Education, Nursing/methods , Humans , Planning TechniquesABSTRACT
Kainic acid-induced lesions (KAL) of the striatum produce body weight and regulatory deficits in the rat. Unlike lateral hypothalamic rats. KAL rats drink more during food deprivation and eat more afterwards as compared to both baseline conditions and control rats. The present study investigated these effects further. As in previous studies, food deprivation was found to cause polydipsia and increased postdeprivational food intake in the KAL animal. Urination and defecation, often used as an index of emotionality, were also found to increase under these conditions. When the antidiuretic hormone vasopressin was injected, all of these differences remained with the exception of postdeprivational feeding--KAL rats no longer ate more than controls. These findings suggest that psychogenic factors--but not hormonal influences--may play a primary role in the regulatory peculiarities seen in the KAL rat.
Subject(s)
Corpus Striatum/drug effects , Drinking Behavior/drug effects , Emotions/drug effects , Feeding Behavior/drug effects , Kainic Acid/pharmacology , Animals , Defecation/drug effects , Diuresis/drug effects , Eliminative Behavior, Animal/drug effects , Male , Rats , Rats, Inbred Strains , Vasopressins/pharmacologyABSTRACT
In order better to interpret their physiological role in rat spinal cord, we characterized binding sites of [3H]WB-4101 and [3H]p-aminoclonidine ( [3H] PAC), and determined their regional distribution. These binding sites have characteristics required for, respectively, alpha 1 and alpha 2 receptors of norepinephrine. Binding to these sites is saturable, with Kd values of 0.38 nM and 35 nM for high and low affinity binding sites respectively of [3H]WB-4101; and 1.7 nM, for a single binding site of [3H]PAC. For whole cord, Bmax values are 52 and 320 (high and low affinity sites respectively); and 21 fmol/mg protein. Catecholamines compete stereoselectively for these sites, while selected noradrenergic agents compete with an order of potency corresponding to their relative activity at the alpha 1 and alpha 2 receptors. We conclude that spinal alpha 1 and alpha 2 binding sites have the same pharmacologic properties as corresponding peripheral sites. The alpha 2 and, to a lesser degree, the alpha 1 binding sites vary in concentration with region. Our results support the contention that alpha 2 binding sites subserve neuronal function in the spinal cord.
