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5.
Hepatogastroenterology ; 49(47): 1333-9, 2002.
Article in English | MEDLINE | ID: mdl-12239938

ABSTRACT

BACKGROUND/AIMS: To determine the alterations in coagulation and fibrinolysis occurring in patients treated with the liver dialysis device. METHODOLOGY: Patients with advanced liver disease treated with the liver dialysis device were studied immediately before and after the liver dialysis device treatment. SETTING: A university hospital intensive care unit. PATIENTS: Thirteen consecutive patients with advanced liver disease being evaluated for or awaiting liver transplantation. INTERVENTION: 4-6 hours of liver dialysis treatment for management of hepatic encephalopathy. OUTCOME MEASURES: A panel of coagulation and anticoagulation factors, as well as fibrinolytic and anti-fibrinolytic factors plus measures of activation of inflammation and soluble adhesion factors. RESULTS: The liver dialysis device used was found to be associated with activation of both coagulation and fibrinolytic pathways, activation of inflammation reactants, and an increase in sL-selectin levels. CONCLUSIONS: Liver dialysis device activates both coagulant and fibrinolytic pathways, activates inflammatory response, but these responses are limited to the vascular compartment by an increase in sL-selectin levels.


Subject(s)
Fibrinolysis , Hemofiltration/methods , Hemostasis , Liver Diseases/therapy , Aged , Biomarkers , Blood Coagulation , Dialysis/instrumentation , Female , Hemofiltration/instrumentation , Humans , Liver Diseases/physiopathology , Male , Middle Aged
6.
Head Neck ; 24(3): 301-6, 2002 Mar.
Article in English | MEDLINE | ID: mdl-11891964

ABSTRACT

BACKGROUND: Ipsilateral salivary gland tumors of different histologic types are rare and make up less than 0.3% of all salivary gland neoplasms. Only nine cases of synchronous benign and malignant ipsilateral parotid gland tumors have been described in the literature. METHODS: Two additional cases of synchronous benign and malignant neoplasms in the parotid gland are reported and discussed with a review of literature. RESULTS: Our first case describes a pleomorphic adenoma and a salivary duct carcinoma, an entity not previously reported in the literature. The second case documents the most common benign and malignant ipsilateral parotid gland neoplasm reported in this case series, a Warthin's tumor and a mucoepidermoid carcinoma. CONCLUSIONS: Synchronous salivary gland tumors exhibiting both benign and malignant components are uncommonly observed, with only nine cases published to date. We describe two additional cases of a synchronous benign and malignant ipsilateral parotid gland tumor.


Subject(s)
Carcinoma/pathology , Neoplasms, Multiple Primary/pathology , Salivary Gland Neoplasms/pathology , Adenolymphoma/pathology , Adenoma, Pleomorphic/pathology , Aged , Carcinoma, Mucoepidermoid/pathology , Female , Humans , Middle Aged , Parotid Neoplasms/pathology , Salivary Ducts
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