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J Voice ; 17(4): 589-95, 2003 Dec.
Article in English | MEDLINE | ID: mdl-14740939

ABSTRACT

Medialization thyroplasty (type I) has become the gold standard to improve glottic closure due to unilateral vocal fold paralysis. A newer injection method utilizing homologous collagen from cadaveric human tissue has been described as an attractive alternative as no donor site is required, there is a very low risk of hypersensitivity, and the intact, acellular collagen fibers may suffer a reduced long-term reabsorption rate. Preliminary results on eight patients comparing presurgical and postsurgical parameters (perceptual, stroboscopic, acoustic, and aerodynamic) revealed comparable results when compared with a control group of individuals, age- and sex-matched, that had undergone standard medialization thyroplasty (type I). Further study is needed to assess the long-term results with this minimally invasive method of vocal fold medialization.


Subject(s)
Collagen/administration & dosage , Glottis/physiopathology , Vocal Cord Paralysis/surgery , Vocal Cords/surgery , Voice Disorders/surgery , Adult , Aged , Aged, 80 and over , Biocompatible Materials/administration & dosage , Case-Control Studies , Female , Humans , Injections , Male , Middle Aged , Otorhinolaryngologic Surgical Procedures , Speech Acoustics , Speech Production Measurement , Treatment Outcome , Vocal Cord Paralysis/complications , Voice Disorders/etiology
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